How to win lane as Teemo against Vayne · 57.01% win rate over 1,191 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Teemo | Vayne auto-attacks to stack Silver Bolts but cannot proc W through Blinding Shot — she loses the very mechanic her kit is built around at level 1, so you set the poke tone immediately. |
| Level 2 | Teemo | With Q and Toxic Shot both available, every Vayne trade attempt eats a blind and a poison stack simultaneously — she cannot win a two-hit window against you at level 2. |
| Level 3 | Teemo | Full kit online and Vayne has no answer to your poke range: she must walk in, she must auto, and your Q deletes her W proc every time she tries. |
| Levels 4-5 | Teemo | Q at max rank and mushrooms on every Tumble angle make Levels 4-5 a trap maze she cannot navigate safely — she is either eating poison or stepping on a shroom any time she contests. |
| Level 6 | Teemo | Noxious Trap placement accelerates and Final Hour does not let her dodge mushrooms she cannot see — shroom her entire side of the lane and the all-in is yours on Condemn's cooldown. |
| First item | Teemo | Liandry's DoT combined with Toxic Shot stacks burns Vayne to critical HP in one trade cycle, and your shroom perimeter denies the Tumble-kite she needs to survive it. |
| Two+ items | Vayne | Silver Bolts true damage and Final Hour invisibility reverse the matchup at two items — respect the window, play for side-lane shroom control and picks, not direct duels. |
Vayne top is your dream matchup early — she has no gap-close, no hard CC outside Condemn, and Silver Bolts requires three autos to proc, every one of which you can blind. At level 1, open with an auto to proc Toxic Shot poison before she can stack anything, then immediately Q-blind when she retaliates. She cannot proc W through the blind, so you get poison ticking while she wastes the stack. At level 2 you compound this with Move Quick: poke, Q when she follows up, and W out before she can angle a Condemn. Never stand near walls even this early — Condemn is her only kill threat and she will burn it the moment you give her an angle.
The full Teemo vs Vayne report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
Become a Founding Member — $1.99/month →🔒 Secure checkout · 💰 7-day money-back guarantee · ✋ Cancel anytime
Early Access price — $3.99/month for new members after launch.
Playing the other side? Vayne vs Teemo guide →
All Teemo top lane matchups →