How to win lane as Vayne against Samira · 51.66% win rate over 4,117 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Level 1 is even as neither of you has a committal all-in yet. |
| Level 2 | Even / skill | Level 2 stays skill-based with her poke offset by your Tumble spacing. |
| Level 3 | Even / skill | Level 3 remains a coin-flip decided by whether you deny her E-dash range. |
| Levels 4-5 | Even / skill | Levels 4-5 stay even, her melee threat balanced by your kiting. |
| Level 6 | Samira | Level 6 favors Samira because Inferno Trigger plus support CC is a lethal all-in you can't yet answer. |
| First item | Samira | First item favors Samira as her Shieldbow lifesteal and reset burst peak before your scaling. |
| Two+ items | Vayne | At 2+ items you win: the melee-bound Samira gets kited and Condemned by Final Hour and Silver Bolts. |
Levels 1-4 are skill-based: Samira's Flair pokes but she needs melee to snowball, so if you Tumble to hold max range and hug minions you farm even and deny her dash gap-closes.
The full Vayne vs Samira report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Samira vs Vayne guide →
All Vayne bot lane (adc) matchups →