How to win lane as Vayne against Varus · 54.93% win rate over 1,855 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Varus | Varus's superior auto range and Piercing Arrow poke own the level 1 last-hitting duel. |
| Level 2 | Varus | At level 2 his W blight and Q let him tax every CS attempt you make. |
| Level 3 | Varus | Level 3 gives Varus full poke-plus-blight combo pressure you can't answer yet. |
| Levels 4-5 | Varus | Through levels 4-5 his sustained Q poke keeps you shoved and low. |
| Level 6 | Varus | At 6 his Chain of Corruption root plus support follow-up outkills your fresh Final Hour. |
| First item | Vayne | With one item Vayne's three-hit true damage finally overpowers Varus's squishy body. |
| Two+ items | Vayne | In the 2+ item teamfight phase Vayne's kiting and true damage hard-outscale Varus. |
Varus dominates levels 1-2: his auto range and Piercing Arrow poke you every time you step up to last-hit, so farm from max range behind your caster minions and only Tumble to secure CS or dodge a charged Q, never to trade.
The full Vayne vs Varus report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
Become a Founding Member — $1.99/month →🔒 Secure checkout · 💰 7-day money-back guarantee · ✋ Cancel anytime
Early Access price — $3.99/month for new members after launch.
Playing the other side? Varus vs Vayne guide →
All Vayne bot lane (adc) matchups →