How to win lane as Samira against Vayne · 52.43% win rate over 4,158 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Samira | Vayne has no waveclear or ranged trade, so you win the level-1 shove and CS denial. |
| Level 2 | Samira | At level 2 your extra basic keeps her permanently zoned with no Tumble kill threat. |
| Level 3 | Samira | Level 3 gives you full kit to punish her before she has any scaling online. |
| Levels 4-5 | Samira | Through 4-5 you hold Style stacks off her minions while she can't disengage. |
| Level 6 | Samira | Your level-6 Inferno Trigger plus support CC out-all-ins a Vayne with no escape until her own ult. |
| First item | Samira | On one item you delete her before three Silver Bolts stack, so first-item is yours. |
| Two+ items | Vayne | At two-plus items Vayne's Final Hour stealth, true damage and Condemn kiting flip the fight to her. |
You out-stat Vayne at every early level: she has no waveclear and can't contest your Q pokes, so you push the wave, deny her CS under tower, and use W to erase her Tumble follow-up and refill Style, snowballing before her scaling exists.
The full Samira vs Vayne report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Vayne vs Samira guide →
All Samira bot lane (adc) matchups →