How to win lane as Lillia against Vayne · 45.71% win rate (676 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15
Her dash interrupts your jog — hold E for the engage and sleep the dive at 6.
Track: Vayne's E — Condemn (20–12s cooldown). Wall-stun — never fight her with terrain at your back.
Read from Lillia's seat: which stage windows this plan plays for against Vayne.
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | You have one ability and no kite chain — concede the opening, last-hit with the tip of Q, and don't feed her early autos. |
| Level 2 | Vayne | She can already tumble-kite and auto you while your Q hops fall short — farm safe, you have no real trade yet. |
| Level 3 | Lillia | With the E slow plus a full Q sweetspot and Dream Dust burn, your stacked move speed finally outruns her tumble and chips her if she walks up. |
| Levels 4-5 | Even / skill | You can grind her when she steps to CS, but her autos still out-range your hops — it's a genuine coinflip on spacing. |
| Level 6 | Lillia | Lilting Lullaby can sleep her mid-poke for a gank, but the delay means you own this only with a jungler — solo, she tumbles free. |
| First item | Vayne | Your Liandry's/Riftmaker spike is real, but it's exactly where her Silver Bolts and Q+W+E kite start deleting you first. |
| Two+ items | Vayne | Full-build Vayne true-damages through any HP you stack and condemns you out of every kite — this is her lane, play for the map, not the duel. |
Level 1 you have nothing — one ability, no kite chain — so just farm with the tip of Q from max range and eat the auto poke; do not walk up. By Level 3 your stacked Q move speed and the E slow finally let you close, so flick the E seed to slow her, hit the outer Q sweetspot, and let Dream Dust burn while you skip away before she can tumble-reset. Never throw E straight at her — she just tumbles it and punishes the cooldown.
Pooled Emerald+ win rates from Lillia's side, sampled July 2026.
The full Lillia vs Vayne report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Vayne, slightly — Lillia wins 45.71% of 676 games; winnable with the right plan.
Mostly — Vayne has a small statistical edge (54.29% win rate), but execution decides this lane far more than the pick does.
No — if anything Vayne has the slight edge (Lillia wins 45.71%), though it stays close.
Lillia takes Grasp of the Undying on the Resolve tree with Demolish, Second Wind and Overgrowth, and Sorcery secondary (Transcendence and Celerity) vs Vayne.
Start Doran's Ring + 2 Health Potions and back for Fated Ashes (≈900g) — burn comes online. Build Liandry's Torment first, then Riftmaker / Rylai's Crystal Scepter, with Plated Steelcaps / Swifties.
Playing the other side? Vayne vs Lillia guide →
All Lillia top lane matchups →
More Lillia top lane matchups: vs Trundle · vs Tryndamere · vs Urgot · vs Vladimir · vs Volibear · vs Warwick