How to win lane as Lissandra against Ryze · 52.89% win rate over 1,681 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Lissandra | Level 1 is Lissandra-favoured because Ryze is immobile and you can freely walk up and poke without fear of a dash. |
| Level 2 | Lissandra | Level 2 stays yours as your Q trade and E threat outpace his mana-limited short-range Q. |
| Level 3 | Lissandra | Level 3 favours you: he has no escape from your E all-in once you have a second point of damage. |
| Levels 4-5 | Lissandra | Levels 4-5 remain Lissandra's because his kiting can't shake your point-and-click W. |
| Level 6 | Lissandra | Level 6 is decisively yours since Frozen Tomb ignores his immobility and denies Realm escapes. |
| First item | Lissandra | At first item your burst kills him before rune-stacks matter, keeping the lead yours. |
| Two+ items | Lissandra | With two-plus items your R still hard-locks him and denies his teamfight Realm, so you stay ahead. |
Levels 1-5 are yours across the board. Ryze is one of the most immobile mids in the game and burns mana fast, so you walk him down with Q pokes and threaten E all-ins on his cooldowns; he has no dash to answer your gap-close, and your point-and-click W means his root-flux kiting never gets to fire cleanly.
The full Lissandra vs Ryze report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Ryze vs Lissandra guide →
All Lissandra mid lane matchups →