How to win lane as Lissandra against Pantheon · 55.29% win rate over 2,232 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Level 1 is even before Pantheon has his W stun to threaten an all-in. |
| Level 2 | Pantheon | Level 2 favors Pantheon: W (Shield Vault) stun into Q lets him start winning all-ins. |
| Level 3 | Pantheon | Level 3 stays his as his empowered Q and passive block let him bully your trades. |
| Levels 4-5 | Pantheon | Levels 4-5 remain Pantheon's window with repeated W-Q all-ins before your R exists. |
| Level 6 | Lissandra | Level 6 flips to you: R negates his combo, letting you survive and lock him mid-engage. |
| First item | Lissandra | First item is yours as his burst falls off while your E-Q-R chain reliably kills him. |
| Two+ items | Lissandra | With 2+ items you dominate: your AoE lockdown and survivability outclass his fading single-target burst. |
Level 1 is even, but from 2 to 5 the lane is Pantheon's. His Q poke and W stun let him all-in repeatedly, and his passive blocks your first spell or auto. Play safe, hold E to disengage his W-Q burst, and refuse melee trades into his empowered Q so his lead stays small.
The full Lissandra vs Pantheon report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Pantheon vs Lissandra guide →
All Lissandra mid lane matchups →