How to win lane as Lissandra against Neeko · 52.95% win rate over 1,135 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Level 1 is even as both trade pokes and Neeko's W lets her slip out of extended exchanges. |
| Level 2 | Even / skill | Level 2 stays skill-based with her Q harass trading roughly against your E-Q. |
| Level 3 | Even / skill | Level 3 remains even since neither has a reliable all-in and her clone muddies engages. |
| Levels 4-5 | Lissandra | Levels 4-5 flip to you: when her W and clone are down she can't escape your E-Q punish. |
| Level 6 | Lissandra | Level 6 is yours because R interrupts her channeled Pop Blossom mid-cast. |
| First item | Lissandra | First item stays yours as your point-and-click R answers any setup-dependent all-in she attempts. |
| Two+ items | Lissandra | With 2+ items you keep the edge: your reliable lockdown beats her combo-reliant burst in fights. |
Levels 1-3 are an even trade fight: Neeko's Q poke and W movement speed let her harass and slip away, but she's immobile once her stealth is down. Match her cooldowns, space with E, and don't overextend into her clone tricks.
The full Lissandra vs Neeko report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Neeko vs Lissandra guide →
All Lissandra mid lane matchups →