Lissandra vs Malzahar — Mid Lane Matchup Guide

How to win lane as Lissandra against Malzahar · 51.91% win rate over 3,275 Emerald+ games · Updated 2026-07-27

Verdict: Lissandra is favoured — Lissandra owns 6 of the 7 game windows to Malzahar's 1. Lissandra wins 51.91% of games vs Malzahar in mid lane (3,275 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1LissandraLevel 1 favors you since Malzahar has no early threat and you can walk up and poke freely.
Level 2LissandraLevel 2 stays yours as your E-Q trade beats his farm-oriented Q and E harass.
Level 3LissandraLevel 3 is yours because you can all-in a defenseless Malzahar before his shield and voidlings scale.
Levels 4-5LissandraLevels 4-5 remain favored: you keep trading and can zone him off CS with no fear of his kit.
Level 6LissandraLevel 6 is still yours as R locks him before Nether Grasp and E-flash beats his suppression window.
First itemLissandraFirst item stays yours through roaming and punishing his inability to follow your waveclear pressure.
Two+ itemsMalzaharWith 2+ items it flips to Malzahar: his point-and-click R, silence, and Zhonya's make him the reliable pick threat.

Early game (levels 1–5)

You own the early game: Malzahar has zero kill pressure at levels 1-3 and just wants to farm, so walk up and E-Q trade freely. His Q is a slow double-line and easy to dodge, letting you win every extended exchange before he shields up.

Read the rest of this matchup

The full Lissandra vs Malzahar report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Malzahar vs Lissandra guide →
All Lissandra mid lane matchups →