Lissandra vs Locke — Mid Lane Matchup Guide

How to win lane as Lissandra against Locke · 50% win rate · Updated 2026-07-27

Verdict: A genuine skill matchup — the favour swings window to window (0 apiece of the 7 stages). Lissandra wins 50% of games vs Locke in mid lane.

Favour timeline — who owns each window

StageFavouredWhy
Level 1Even / skillNo data available, so level 1 is treated as an even skill lane.
Level 2Even / skillLevel 2 defaults to skill-based with no known edge either way.
Level 3Even / skillThrough 3 it stays even pending real matchup information.
Levels 4-5Even / skillAt 4-5 it remains a skill-check with no established favourite.
Level 6Even / skillEven at 6 it's marked even, though your reliable R is a dependable swing.
First itemEven / skillFirst item stays skill-based absent data on his spikes.
Two+ itemsEven / skillLate is even on record, with your teamfight CC as your baseline strength.

Early game (levels 1–5)

No games on record, so treat this as an even, skill-based lane — win it on fundamentals: control the wave with Q, respect the unknown, and don't over-extend without vision or a clear cooldown read.

Read the rest of this matchup

The full Lissandra vs Locke report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Playing the other side? Locke vs Lissandra guide →
All Lissandra mid lane matchups →