The champions that counter Neeko hardest in mid lane are Vladimir (44.67%), Swain (44.96%) and Talon (45.02%) — those are Neeko's own pooled win rates. The easiest matchups are Karma (55.22%), Akshan (53.08%) and Aurelion Sol (53.06%).
46 researched matchup guides for Neeko in mid lane, most-played first. Win rates are Neeko's side, pooled Emerald+ games sampled July 2026.
| Matchup | Win rate | Games | Favour |
|---|---|---|---|
| Neeko vs Sylas | 47.35% | 2,564 | Leans Sylas |
| Neeko vs Viktor | 49.22% | 2,377 | Leans Viktor |
| Neeko vs Ahri | 46.96% | 2,253 | Leans Ahri |
| Neeko vs Syndra | 47.91% | 2,079 | Leans Syndra |
| Neeko vs Yasuo | 51.38% | 1,915 | Leans Neeko |
| Neeko vs Zed | 47.91% | 1,816 | Leans Zed |
| Neeko vs Katarina | 45.42% | 1,755 | Leans Katarina |
| Neeko vs Yone | 48.99% | 1,684 | Leans Yone |
| Neeko vs Akali | 46.77% | 1,546 | Leans Akali |
| Neeko vs Malzahar | 47.65% | 1,469 | Leans Malzahar |
| Neeko vs Twisted Fate | 47.62% | 1,361 | Leans Twisted Fate |
| Neeko vs Lissandra | 47.25% | 1,327 | Leans Lissandra |
| Neeko vs Xerath | 45.87% | 1,282 | Leans Xerath |
| Neeko vs Fizz | 45.61% | 1,252 | Leans Fizz |
| Neeko vs Hwei | 48.67% | 1,208 | Leans Hwei |
| Neeko vs Galio | 48.52% | 1,183 | Leans Galio |
| Neeko vs LeBlanc | 50.6% | 1,170 | Even |
| Neeko vs Lux | 46.19% | 1,113 | Leans Lux |
| Neeko vs Vladimir | 44.67% | 1,097 | Vladimir favoured |
| Neeko vs Diana | 48.61% | 1,080 | Leans Diana |
| Neeko vs Ryze | 52.82% | 816 | Leans Neeko |
| Neeko vs Vex | 47.75% | 798 | Leans Vex |
| Neeko vs Mel | 50.58% | 785 | Even |
| Neeko vs Naafiri | 48.53% | 783 | Leans Naafiri |
| Neeko vs Veigar | 47.3% | 778 | Leans Veigar |
| Neeko vs Orianna | 49.02% | 767 | Leans Orianna |
| Neeko vs Ekko | 46.17% | 756 | Leans Ekko |
| Neeko vs Akshan | 53.08% | 748 | Leans Neeko |
| Neeko vs Irelia | 47.63% | 718 | Leans Irelia |
| Neeko vs Zoe | 47.31% | 687 | Leans Zoe |
| Neeko vs Talon | 45.02% | 682 | Leans Talon |
| Neeko vs Kassadin | 46.77% | 635 | Leans Kassadin |
| Neeko vs Aurora | 51.68% | 625 | Leans Neeko |
| Neeko vs Anivia | 49.19% | 618 | Leans Anivia |
| Neeko vs Qiyana | 47.1% | 535 | Leans Qiyana |
| Neeko vs Annie | 45.96% | 507 | Leans Annie |
| Neeko vs Cassiopeia | 50.49% | 402 | Even |
| Neeko vs Pantheon | 50.14% | 367 | Even |
| Neeko vs Aurelion Sol | 53.06% | 360 | Leans Neeko |
| Neeko vs Karma | 55.22% | 355 | Neeko favoured |
| Neeko vs Azir | 49.71% | 354 | Even |
| Neeko vs Taliyah | 51.7% | 323 | Leans Neeko |
| Neeko vs Ziggs | 46.4% | 319 | Leans Ziggs |
| Neeko vs Brand | 49.81% | 263 | Even |
| Neeko vs Swain | 44.96% | 258 | Swain favoured |
| Neeko vs Locke | — | — | — |