Neeko vs Karma — Mid Lane Matchup Guide

How to win lane as Neeko against Karma · 55.49% win rate over 319 Emerald+ games · Updated 2026-07-27

Verdict: Winnable despite the lane — Karma owns 4 of the 7 game windows to Neeko's 3, yet the win rate favours Neeko: survive their windows and the game is yours. Neeko wins 55.49% of games vs Karma in mid lane (319 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1KarmaLevel 1 Karma out-ranges you and threatens early Q poke you can't answer.
Level 2KarmaLevel 2 her superior range keeps chunking you before your combo exists.
Level 3KarmaLevel 3 her Mantra-empowered rooting Inner Flame dominates the poke war.
Levels 4-5KarmaLevels 4-5 she still controls the lane with long-range RQ roots and shields.
Level 6NeekoLevel 6 Pop Blossom flips it: she has no escape from your all-in once Mantra is spent.
First itemNeekoAt first item your rooted combo kills her before her single empowered cast returns.
Two+ itemsNeekoTwo-plus items in your R AoE and flanks out-teamfight her low-range peel.

Early game (levels 1–5)

Karma owns levels 1-4 outright: her Mantra empowers Inner Flame into a long-range rooting nuke from level 3, and she out-pokes and out-ranges your entire pre-6 kit. Don't contest the caster line for CS you can't safely take; hold under tower, dodge her Q, and give up minor plates rather than eat RQ chunks.

Read the rest of this matchup

The full Neeko vs Karma report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Karma vs Neeko guide →
All Neeko mid lane matchups →

Also played in: Top Lane · Support