Karma — Mid Lane Matchup Guides

46 researched matchup guides for Karma in mid lane.

Karma vs Ahri Karma vs Akali Karma vs Akshan Karma vs Anivia Karma vs Annie Karma vs Aurelion Sol Karma vs Aurora Karma vs Azir Karma vs Brand Karma vs Cassiopeia Karma vs Diana Karma vs Ekko Karma vs Fizz Karma vs Galio Karma vs Hwei Karma vs Irelia Karma vs Kassadin Karma vs Katarina Karma vs LeBlanc Karma vs Lissandra Karma vs Locke Karma vs Lux Karma vs Malzahar Karma vs Mel Karma vs Naafiri Karma vs Neeko Karma vs Orianna Karma vs Pantheon Karma vs Qiyana Karma vs Ryze Karma vs Swain Karma vs Sylas Karma vs Syndra Karma vs Taliyah Karma vs Talon Karma vs Twisted Fate Karma vs Veigar Karma vs Vex Karma vs Viktor Karma vs Vladimir Karma vs Xerath Karma vs Yasuo Karma vs Yone Karma vs Zed Karma vs Ziggs Karma vs Zoe

MatchupCoach.gg — Challenger-level matchup coaching for every champion, every lane. All matchup guides · Open the interactive coach
Updated 2026-07-27. MatchupCoach.gg isn't endorsed by Riot Games.