How to win lane as Karma against Vladimir · 47.2% win rate over 125 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Karma | Karma's poke and shield dominate lane while Vladimir has no early combo threat |
| Level 2 | Karma | Same dynamic continues as Vladimir is still farming for scaling, not fighting |
| Level 3 | Karma | Karma's poke and shield still win exchanges through this window |
| Levels 4-5 | Karma | Karma's completed item spike lets poke output outpace Vladimir's HP-cost scaling |
| Level 6 | Vladimir | Vladimir's Hemoplague and Pool combo create a real all-in threat that favors him at 6 |
| First item | Karma | Karma's item lead restores the poke-war advantage after the level-6 window passes |
| Two+ items | Vladimir | A scaled Vladimir's Hemoplague reset damage in teamfights outweighs Karma's shield mitigation |
Vladimir is a farming champion before his combo comes online — his healing sustain is passive-based and doesn't offset your consistent poke, so Inner Flame and Inspire let you win the exchanges and zone him off CS through level 5.
The full Karma vs Vladimir report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Vladimir vs Karma guide →
All Karma mid lane matchups →
Also played in: Top Lane