Karma vs Neeko — Mid Lane Matchup Guide

How to win lane as Karma against Neeko · 47.22% win rate over 36 Emerald+ games · Updated 2026-07-27

Verdict: Closer than it looks — Karma owns 4 of the 7 game windows to Neeko's 3, but the win rate still favours Neeko: you have to convert those windows or the game slips away. Karma wins 47.22% of games vs Neeko in mid lane (36 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1KarmaKarma's Mantra-Q poke outranges Neeko's short-range early trades at level 1.
Level 2KarmaKarma's mana sustain lets her keep poking while Neeko has to play more passively.
Level 3KarmaKarma's root and detonation combo keep winning short trades through level 3.
Levels 4-5KarmaKarma's poke lead holds through levels 4-5 as Neeko still lacks a kill tool.
Level 6NeekoNeeko's ultimate gives her a genuine pick and teamfight threat Karma cannot match.
First itemNeekoNeeko's burst and disguise trickery start converting into real kills with items.
Two+ itemsNeekoNeeko's AoE root-and-burst combo dominates late teamfights over Karma's utility-only kit.

Early game (levels 1–5)

Karma's superior poke range and mana sustain via Mantra-Q let her control trades against Neeko's shorter, more mana-hungry early kit.

Read the rest of this matchup

The full Karma vs Neeko report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Neeko vs Karma guide →
All Karma mid lane matchups →

Also played in: Top Lane · Support