Karma vs Anivia — Mid Lane Matchup Guide

How to win lane as Karma against Anivia · 39.13% win rate over 46 Emerald+ games · Updated 2026-07-27

Verdict: Closer than it looks — Karma owns 4 of the 7 game windows to Anivia's 3, but the win rate still favours Anivia: you have to convert those windows or the game slips away. Karma wins 39.13% of games vs Anivia in mid lane (46 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1KarmaLevel 1 you dominate — Anivia's kit does nothing to punish your poke and her egg makes all-ins pointless anyway for you but the trade math still favors your damage.
Level 2KarmaLevel 2 continues in your favor as she's still short-range and vulnerable to Mantra-empowered pokes.
Level 3KarmaLevel 3 you're still ahead, denying her farm and health before her scaling kicks in.
Levels 4-5KarmaLevel 4 remains your window — she has no wall or ultimate yet to threaten you.
Level 6AniviaLevel 5 is your last strong phase before her power spike changes everything at 6.
First itemAniviaAt 6 Anivia's Glacial Storm and wall combo give her zone control and burst that beats your poke-and-shield kit.
Two+ itemsAniviaLate game she continues to dominate through waveclear and one-shot combos your enchanter toolkit can't out-scale.

Early game (levels 1–5)

Levels 1-2 you clearly win — Anivia is slow, has no wall yet, and her egg passive doesn't stop you from denying CS and chipping her with Mantra Q whenever she pushes up.

Read the rest of this matchup

The full Karma vs Anivia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Anivia vs Karma guide →
All Karma mid lane matchups →