The champions that counter Anivia hardest in mid lane are Hwei (45.68%), Diana (46.66%) and Annie (46.94%) — those are Anivia's own pooled win rates. The easiest matchups are Karma (54.44%), Mel (54.39%) and Swain (54.24%).
46 researched matchup guides for Anivia in mid lane, most-played first. Win rates are Anivia's side, pooled Emerald+ games sampled July 2026.
| Matchup | Win rate | Games | Favour |
|---|---|---|---|
| Anivia vs Viktor | 50.38% | 5,866 | Even |
| Anivia vs Ahri | 47.99% | 5,243 | Leans Ahri |
| Anivia vs Syndra | 47.46% | 4,962 | Leans Syndra |
| Anivia vs Sylas | 49.77% | 4,623 | Even |
| Anivia vs Yasuo | 51.83% | 4,233 | Leans Anivia |
| Anivia vs Zed | 49.45% | 4,127 | Even |
| Anivia vs Yone | 51.46% | 3,974 | Leans Anivia |
| Anivia vs Hwei | 45.68% | 3,584 | Leans Hwei |
| Anivia vs Xerath | 47.25% | 3,564 | Leans Xerath |
| Anivia vs Malzahar | 49.18% | 3,457 | Leans Malzahar |
| Anivia vs Katarina | 47.7% | 3,434 | Leans Katarina |
| Anivia vs Vladimir | 51.67% | 3,129 | Leans Anivia |
| Anivia vs Twisted Fate | 49.85% | 3,033 | Even |
| Anivia vs Lux | 50.88% | 2,901 | Leans Anivia |
| Anivia vs Lissandra | 49.83% | 2,753 | Even |
| Anivia vs Ryze | 54.16% | 2,727 | Leans Anivia |
| Anivia vs Naafiri | 48.88% | 2,696 | Leans Naafiri |
| Anivia vs Akali | 50.4% | 2,593 | Even |
| Anivia vs Fizz | 49.14% | 2,326 | Leans Fizz |
| Anivia vs Diana | 46.66% | 2,323 | Leans Diana |
| Anivia vs Veigar | 47.82% | 2,273 | Leans Veigar |
| Anivia vs LeBlanc | 51.15% | 2,272 | Leans Anivia |
| Anivia vs Karma | 54.44% | 2,186 | Leans Anivia |
| Anivia vs Galio | 52.31% | 2,101 | Leans Anivia |
| Anivia vs Irelia | 51.52% | 2,077 | Leans Anivia |
| Anivia vs Talon | 48.26% | 1,956 | Leans Talon |
| Anivia vs Akshan | 51.16% | 1,851 | Leans Anivia |
| Anivia vs Mel | 54.39% | 1,846 | Leans Anivia |
| Anivia vs Ekko | 51.46% | 1,714 | Leans Anivia |
| Anivia vs Orianna | 53.48% | 1,608 | Leans Anivia |
| Anivia vs Aurora | 49.4% | 1,583 | Even |
| Anivia vs Kassadin | 50.96% | 1,568 | Leans Anivia |
| Anivia vs Zoe | 50.43% | 1,509 | Even |
| Anivia vs Vex | 51.85% | 1,483 | Leans Anivia |
| Anivia vs Qiyana | 48.79% | 1,287 | Leans Qiyana |
| Anivia vs Annie | 46.94% | 1,176 | Leans Annie |
| Anivia vs Pantheon | 50.69% | 1,093 | Even |
| Anivia vs Ziggs | 48.82% | 1,063 | Leans Ziggs |
| Anivia vs Brand | 51.89% | 1,056 | Leans Anivia |
| Anivia vs Swain | 54.24% | 1,025 | Leans Anivia |
| Anivia vs Aurelion Sol | 50.1% | 942 | Even |
| Anivia vs Cassiopeia | 50.81% | 925 | Leans Anivia |
| Anivia vs Taliyah | 47.86% | 794 | Leans Taliyah |
| Anivia vs Azir | 50.6% | 751 | Even |
| Anivia vs Neeko | 50.81% | 618 | Leans Anivia |
| Anivia vs Locke | — | — | — |