Lissandra vs Qiyana — Mid Lane Matchup Guide

How to win lane as Lissandra against Qiyana · 53.39% win rate over 1,742 Emerald+ games · Updated 2026-07-27

Verdict: Lissandra is favoured — Lissandra owns 3 of the 7 game windows. Lissandra wins 53.39% of games vs Qiyana in mid lane (1,742 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Even / skillLevel 1 is even skill — neither of you has a real all-in and Qiyana's element empowerment only matters once she can trade with it.
Level 2Even / skillLevel 2 stays skill as her empowered Q trades are answered by your Q waveclear and safe positioning.
Level 3Even / skillLevel 3 is a coin-flip skill window where her dash all-in and your W disengage cancel out.
Levels 4-5Even / skillLevels 4-5 remain skill: she threatens reset kills but your point-and-click W denies her the clean burst.
Level 6LissandraLevel 6 favours Lissandra because Frozen Tomb hard-counters her dive and can self-peel or lock her mid-combo.
First itemLissandraAt first item your gap-close stun chain lets you lock her before she empowers, so the item spike is yours.
Two+ itemsLissandraWith two-plus items your AoE ult swings teamfights far harder than her single-target reset assassinations.

Early game (levels 1–5)

Levels 1-4 are skill: Qiyana has strong element-empowered trades but you have safe waveclear with Q and a point-and-click W to stop her dash windows, so trade back when her element is on cooldown and don't let her freerange the brush.

Read the rest of this matchup

The full Lissandra vs Qiyana report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

Become a Founding Member — $1.99/month →

🔒 Secure checkout · 💰 7-day money-back guarantee · ✋ Cancel anytime
Early Access price — $3.99/month for new members after launch.

Related guides

Playing the other side? Qiyana vs Lissandra guide →
All Lissandra mid lane matchups →