How to win lane as Pantheon against Lissandra · 50.74% win rate over 339 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Pantheon | Level 1 Pantheon's base damage and Q out-trade the mana-limited early Lissandra. |
| Level 2 | Pantheon | Level 2-3 the W stun all-in punishes Lissandra before she can trade back. |
| Level 3 | Pantheon | By level 4 Pantheon keeps priority as Lissandra still lacks her key defensive tool. |
| Levels 4-5 | Pantheon | Level 5 Pantheon holds full kill pressure before her R comes online. |
| Level 6 | Lissandra | At level 6 Lissandra's self-cast R stasis negates Pantheon's burst and swings the 1v1 to her. |
| First item | Pantheon | Post-6 Pantheon's W interrupt and roams claw back tempo, giving him the edge in the skirmish window. |
| Two+ items | Lissandra | Late, Lissandra's tanky AoE CC survives Pantheon's engage and locks down his team, taking the game. |
Pantheon out-trades Lissandra in the early laning phase: his Q poke and W stun let him win short trades before she has the mana and cooldowns to fight back. Lissandra's early damage and self-peel are limited before 6, so Pantheon should be aggressive at levels 2-3 and look to force her low or out of lane. Deny her the passive scaling she wants.
The full Pantheon vs Lissandra report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Lissandra vs Pantheon guide →
All Pantheon mid lane matchups →