How to win lane as Vayne against Sion · 52.27% win rate over 1,653 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Vayne | You dodge Sion's slow Q and out-poke him at level 1. |
| Level 2 | Vayne | At 2 you keep punishing his whiffed knockups. |
| Level 3 | Vayne | Third-stack true damage at 3 melts his tank HP. |
| Levels 4-5 | Vayne | You sidestep Q and E through 4-5 with Tumble. |
| Level 6 | Vayne | Final Hour and Condemn shut down his ult at 6. |
| First item | Vayne | First-item true damage outpaces his shield and growth. |
| Two+ items | Vayne | Late-game your W ignores his HP and he can't stick. |
Sion can only threaten you with a fully-charged Q, which is easy to sidestep; poke his walk-ups with Q-auto and take the CS lead at levels 1-2.
The full Vayne vs Sion report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Sion vs Vayne guide →
All Vayne top lane matchups →