Vayne vs Quinn — Top Lane Matchup Guide

How to win lane as Vayne against Quinn · 49.75% win rate over 408 Emerald+ games · Updated 2026-07-27

Verdict: Quinn is favoured — Quinn owns 6 of the 7 game windows to Vayne's 1. Play it patient and win your windows. Vayne wins 49.75% of games vs Quinn in top lane (408 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1QuinnQuinn's Blinding Assault (Q) out-ranges you and pokes freely at level 1.
Level 2QuinnAt 2 her extra AA range and Harrier procs keep chipping you down.
Level 3QuinnVault (E) at 3 resets her auto and shoves you off the wave.
Levels 4-5QuinnLevels 4-5 her lethality poke keeps you pinned under tower.
Level 6QuinnBehold, Harrier (R) at 6 lets her dive or roam while you can't react.
First itemQuinnFirst item her burst still kills you before Silver Bolts ramps.
Two+ itemsVayneAt 2+ items Silver Bolts true damage and Condemn flip the 1v1 to you.

Early game (levels 1–5)

Quinn out-ranges and out-pokes you at level 1-2; her Blinding Assault (Q) chips you for free and Harrier procs sting. Farm passively, don't walk up.

Read the rest of this matchup

The full Vayne vs Quinn report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Playing the other side? Quinn vs Vayne guide →
All Vayne top lane matchups →