How to win lane as Vayne against Ryze · 57.38% win rate over 894 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Vayne | Ryze is immobile at 1, so your Silver Bolts and mobility win. |
| Level 2 | Vayne | At 2 your DPS keeps out-trading his short-range poke. |
| Level 3 | Vayne | Level 3 your Tumble and W let you walk him down. |
| Levels 4-5 | Vayne | Levels 4-5 you dictate trades as long as you dodge Rune Prison. |
| Level 6 | Even / skill | Level 6 evens out on his waveclear and burst combo. |
| First item | Vayne | First item your true damage shreds his low health faster than he pokes. |
| Two+ items | Vayne | At 2+ items Final Hour and Condemn delete him in the 1v1. |
You win the early game; Ryze is immobile and your Silver Bolts (W) true damage plus Tumble mobility let you pressure his short range. Just respect his Overload (Q) poke and don't facetank Rune Prison.
The full Vayne vs Ryze report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Ryze vs Vayne guide →
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