How to win lane as Vayne against Camille · 52.05% win rate (1,001 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15
Condemn her hookshot engage, tumble the E, and %-true out-trades her sustain — she can't stick to you.
Track: Camille's E — Hookshot (16–12s cooldown). Her engage/stun. Condemn the follow-up.
Read from Vayne's seat: which stage windows this plan plays for against Camille.
This is Vayne's own plan; across 1,001 pooled games the lane is leaning Vayne.
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Camille | Camille's Q double-cast carries true damage and out-trades you at 1. |
| Level 2 | Camille | At 2 her shield and E burst still win short exchanges. |
| Level 3 | Camille | Level 3 her wall-dive engage lets her pick trades against you. |
| Levels 4-5 | Even / skill | At 4-5 your AS spike plus a Condemn on her E-dash swings trades to you. |
| Level 6 | Camille | Hextech Ultimatum at 6 traps you and reduces her damage taken. |
| First item | Even / skill | Her Sheen-Q first-item spike out-trades your unfinished Bork. |
| Two+ items | Vayne | With 2+ items and Final Hour your shred and kiting outscale her. |
Camille wins levels 1-3: her Q double-cast carries the true damage and out-trades you before Silver Bolts is online, and her passive shield blunts your autos. Don't get walled by her Hookshot.
Pooled Emerald+ win rates from Vayne's side, sampled July 2026.
The full Vayne vs Camille report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Vayne, slightly — a 52.05% win rate edge over 1,001 games; execution can flip it.
Mostly — Vayne has a small statistical edge (52.05% win rate), but execution decides this lane far more than the pick does.
Not a hard counter — Vayne has a slight edge (52.05% win rate), and play quality decides the rest.
Vayne takes Lethal Tempo on the Precision tree with Triumph, Legend: Alacrity and Last Stand, and Resolve secondary (Bone Plating and Unflinching) vs Camille.
Start Doran's Blade + Health Potion and back for Executioner's Calling (≈800g) — cuts her healing. Build Blade of the Ruined King (%HP duel spike) first, then Phantom Dancer, with Plated Steelcaps.
Playing the other side? Camille vs Vayne guide →
All Vayne top lane matchups →
More Vayne top lane matchups: vs Akshan · vs Ambessa · vs Aurora · vs Cassiopeia · vs Cho'Gath · vs Darius