How to win lane as Vayne against Camille · 52.05% win rate over 1,001 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Camille | Camille's Q double-cast and E true damage out-trade level-1 Vayne. |
| Level 2 | Camille | At 2 her shield and E burst still win short exchanges. |
| Level 3 | Camille | Level 3 her wall-dive engage lets her pick trades against you. |
| Levels 4-5 | Vayne | At 4-5 your AS spike plus a Condemn on her E-dash swings trades to you. |
| Level 6 | Camille | Hextech Ultimatum at 6 traps you and reduces her damage taken. |
| First item | Camille | Her Sheen-Q first-item spike out-trades your unfinished Bork. |
| Two+ items | Vayne | With 2+ items and Final Hour your shred and kiting outscale her. |
Camille wins levels 1-3: her Q double-cast and E true damage out-trade you before Silver Bolts online, and her shield blunts your autos. Give up melee CS and don't get walled by her Hookshot.
The full Vayne vs Camille report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Camille vs Vayne guide →
All Vayne top lane matchups →