The champions that counter Nautilus hardest in support are Taric (43.21%), Rell (44.91%) and Leona (45.76%) — those are Nautilus's own pooled win rates. The easiest matchups are Yuumi (55.64%), Pyke (53.73%) and Karma (53.63%).
35 researched matchup guides for Nautilus in support, most-played first. Win rates are Nautilus's side, pooled Emerald+ games sampled July 2026.
| Matchup | Win rate | Games | Favour |
|---|---|---|---|
| Nautilus vs Thresh | 47.79% | 40,101 | Leans Thresh |
| Nautilus vs Seraphine | 47.98% | 28,226 | Leans Seraphine |
| Nautilus vs Senna | 46.85% | 23,862 | Leans Senna |
| Nautilus vs Leona | 45.76% | 23,692 | Leans Leona |
| Nautilus vs Braum | 45.8% | 23,109 | Leans Braum |
| Nautilus vs Lulu | 51.82% | 22,611 | Leans Nautilus |
| Nautilus vs Pyke | 53.73% | 21,592 | Leans Nautilus |
| Nautilus vs Karma | 53.63% | 20,699 | Leans Nautilus |
| Nautilus vs Nami | 50.94% | 18,564 | Leans Nautilus |
| Nautilus vs Lux | 52.94% | 17,386 | Leans Nautilus |
| Nautilus vs Bard | 51.09% | 16,483 | Leans Nautilus |
| Nautilus vs Morgana | 48.03% | 15,167 | Leans Morgana |
| Nautilus vs Milio | 51.53% | 15,146 | Leans Nautilus |
| Nautilus vs Yuumi | 55.64% | 14,384 | Nautilus favoured |
| Nautilus vs Rell | 44.91% | 13,971 | Rell favoured |
| Nautilus vs Alistar | 48.56% | 13,363 | Leans Alistar |
| Nautilus vs Blitzcrank | 50.51% | 12,943 | Even |
| Nautilus vs Soraka | 48.78% | 11,114 | Leans Soraka |
| Nautilus vs Xerath | 50.69% | 11,004 | Even |
| Nautilus vs Vel'Koz | 51.42% | 10,586 | Leans Nautilus |
| Nautilus vs Janna | 48.33% | 9,149 | Leans Janna |
| Nautilus vs Rakan | 48.88% | 8,877 | Leans Rakan |
| Nautilus vs Swain | 49.25% | 8,099 | Leans Swain |
| Nautilus vs Tahm Kench | 47.38% | 7,884 | Leans Tahm Kench |
| Nautilus vs Zilean | 49.82% | 7,576 | Even |
| Nautilus vs Sona | 49.23% | 7,343 | Leans Sona |
| Nautilus vs Hwei | 48.8% | 7,166 | Leans Hwei |
| Nautilus vs Brand | 50.58% | 7,070 | Even |
| Nautilus vs Galio | 50.41% | 6,957 | Even |
| Nautilus vs Poppy | 50.68% | 6,936 | Even |
| Nautilus vs Zyra | 51.4% | 5,364 | Leans Nautilus |
| Nautilus vs Taric | 43.21% | 4,444 | Taric favoured |
| Nautilus vs Maokai | 48.43% | 4,322 | Leans Maokai |
| Nautilus vs Neeko | 51.02% | 4,153 | Leans Nautilus |
| Nautilus vs Renata Glasc | 48.9% | 3,190 | Leans Renata Glasc |