Annie vs Lissandra — Mid Lane Matchup Guide

How to win lane as Annie against Lissandra · 50.05% win rate (2,358 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: A genuine skill matchup — 50.05% win rate over 2,358 games, decided window to window rather than at champion select.

At a glance

She out-ranges you — but a stocked stun makes every step into your Flash radius a coin she can't afford to flip.

Track: Lissandra's E — Glacial Path (Claw, 24–12s cooldown). Her engage and escape in one button — she is immobile while it is down.

Do

  • Farm Q refunds and stack quietly
  • Hold the four-stack glow as zone control
  • Flash-R the one overstep she donates

Don't

  • Trade into her range with stacks down
  • Burn the stun on poke she can answer
  • Walk up unstacked to contest CS

Runes & build vs Lissandra

Start
Doran's Ring + 2 Health Potions
First back
Lost Chapter (≈1300g) — refunds become a war chest
First item
Stormsurge / Luden's
Then
Shadowflame
Boots
Sorcerer's Shoes / Mercury's Treads
Runes
Electrocute (Domination): Cheap Shot, Grisly Mementos, Ultimate Hunter · Sorcery: Manaflow Band, Scorch · Shards: Adaptive Force, Adaptive Force, Health

Favour timeline — the windows in Annie's game plan

Read from Annie's seat: which stage windows this plan plays for against Lissandra.

This is Annie's own plan; across 2,358 pooled games the lane is even.

StageFavouredWhy
Level 1Even / skillLevel 1 is an even skill matchup as Lissandra's poke lacks the burst to truly punish you.
Level 2Even / skillLevel 2 stays skill-dependent since neither side has a clear damage advantage yet.
Level 3Even / skillLevel 3-5 remains a skill matchup — her mobility helps her disengage but doesn't win trades outright.
Levels 4-5Even / skillLevels 4-5 tilt toward you as your growing burst threat starts to outpace her poke damage.
Level 6Even / skillLevel 6 is your peak spike since her self-Tomb only delays your Tibbers combo, not prevents it.
First itemAnnieFirst item still favors you as your burst scaling outpaces her more utility-oriented kit.
Two+ itemsEven / skill2+ items remains yours in the 1v1 sense, even as she becomes a stronger team-fight disruptor.

How to beat Lissandra as Annie: the early game

Levels 1-2 are a skill matchup — Lissandra's Ice Shard poke can chip you at range, but her lack of hard burst means you're not in serious danger if you play around minion aggro. This continues through levels 3-5: her Glacial Path gives her safe repositioning and combo potential, but she still needs to commit close to threaten real damage, giving you stun opportunities if you watch her cooldowns.

Hardest and easiest matchups for Annie in mid lane

Pooled Emerald+ win rates from Annie's side, sampled July 2026.

Hardest

Easiest

Read the rest of this matchup

The full Annie vs Lissandra report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Annie vs Lissandra in mid lane?

Nobody on paper — a 50.05% win rate over 2,358 games makes this a coin flip decided by play, not champion select.

Is Annie vs Lissandra a skill matchup?

Yes — Annie vs Lissandra is a genuine skill matchup: 50.05% win rate, and the favour swings window to window rather than being set at champion select.

Does Annie counter Lissandra?

No hard counter either way — the Annie vs Lissandra win rate is 50.05%, an even lane decided by execution.

What runes does Annie take vs Lissandra?

Annie takes Electrocute on the Domination tree with Cheap Shot, Grisly Mementos and Ultimate Hunter, and Sorcery secondary (Manaflow Band and Scorch) vs Lissandra.

What should Annie build vs Lissandra?

Start Doran's Ring + 2 Health Potions and back for Lost Chapter (≈1300g) — refunds become a war chest. Build Stormsurge / Luden's first, then Shadowflame, with Sorcerer's Shoes / Mercury's Treads.

Related guides

Playing the other side? Lissandra vs Annie guide →
All Annie mid lane matchups →

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