How to win lane as Vayne against Caitlyn · 50.94% win rate over 10,116 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Caitlyn out-ranges you but even play trades neutral at level 1. |
| Level 2 | Even / skill | At 2 it stays skill-based on whether you dodge her Q poke. |
| Level 3 | Even / skill | Level 3 traps threaten you but disciplined spacing keeps it even. |
| Levels 4-5 | Even / skill | Through 4-5 clean CS and trap-dodging hold the lane neutral. |
| Level 6 | Even / skill | Neither ult breaks the even duel at level 6. |
| First item | Even / skill | By one item your closing power offsets her poke for an even trade. |
| Two+ items | Even / skill | With items it stays skill-decided on whether you beat her net kite. |
A skill-decided lane: Caitlyn out-ranges you and threatens Trap-into-Headshot combos, so last-hit from behind minions, never walk onto a trap, and take only free autos when she uses Q on the wave.
The full Vayne vs Caitlyn report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Caitlyn vs Vayne guide →
All Vayne bot lane (adc) matchups →