The champions that counter Caitlyn hardest in bot lane are Ziggs (46.14%), Senna (46.38%) and Nilah (46.44%) — those are Caitlyn's own pooled win rates. The easiest matchups are Varus (52.62%), Corki (52.61%) and Swain (52.03%).
29 researched matchup guides for Caitlyn in bot lane, most-played first. Win rates are Caitlyn's side, pooled Emerald+ games sampled July 2026.
| Matchup | Win rate | Games | Favour |
|---|---|---|---|
| Caitlyn vs Jhin | 48.24% | 94,784 | Leans Jhin |
| Caitlyn vs Ezreal | 50.32% | 84,936 | Even |
| Caitlyn vs Jinx | 47% | 64,538 | Leans Jinx |
| Caitlyn vs Kai'Sa | 50.24% | 54,812 | Even |
| Caitlyn vs Ashe | 48.42% | 50,571 | Leans Ashe |
| Caitlyn vs Senna | 46.38% | 40,347 | Leans Senna |
| Caitlyn vs Lucian | 50.98% | 39,417 | Leans Caitlyn |
| Caitlyn vs Miss Fortune | 49.16% | 34,656 | Leans Miss Fortune |
| Caitlyn vs Seraphine | 47.2% | 32,678 | Leans Seraphine |
| Caitlyn vs Tristana | 49.25% | 30,450 | Leans Tristana |
| Caitlyn vs Aphelios | 50.23% | 27,092 | Even |
| Caitlyn vs Smolder | 49.77% | 22,930 | Even |
| Caitlyn vs Sivir | 49.05% | 22,857 | Leans Sivir |
| Caitlyn vs Ziggs | 46.14% | 22,848 | Leans Ziggs |
| Caitlyn vs Twitch | 47.9% | 21,733 | Leans Twitch |
| Caitlyn vs Vayne | 51.52% | 20,365 | Leans Caitlyn |
| Caitlyn vs Samira | 48.28% | 19,764 | Leans Samira |
| Caitlyn vs Draven | 50.48% | 19,139 | Even |
| Caitlyn vs Varus | 52.62% | 14,009 | Leans Caitlyn |
| Caitlyn vs Zeri | 49.87% | 13,292 | Even |
| Caitlyn vs Xayah | 49.26% | 13,100 | Even |
| Caitlyn vs Veigar | 49.23% | 9,956 | Leans Veigar |
| Caitlyn vs Swain | 52.03% | 8,499 | Leans Caitlyn |
| Caitlyn vs Kalista | 49.93% | 7,491 | Even |
| Caitlyn vs Kog'Maw | 47.98% | 7,247 | Leans Kog'Maw |
| Caitlyn vs Nilah | 46.44% | 4,631 | Leans Nilah |
| Caitlyn vs Corki | 52.61% | 4,208 | Leans Caitlyn |
| Caitlyn vs Karthus | 48.27% | 3,998 | Leans Karthus |
| Caitlyn vs Heimerdinger | 51.14% | 3,084 | Leans Caitlyn |