How to win lane as Vayne against Zac · 52.44% win rate over 698 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Vayne | You own level 1: Zac has no E engage yet, so you freely stack Silver Bolts and win short trades. |
| Level 2 | Zac | At 2 Zac's E slingshot comes online and lets him engage from outside your kite range. |
| Level 3 | Zac | Through 3 his E-into-Q displacement and blob sustain out-trade you. |
| Levels 4-5 | Zac | Across 4-5 his tankiness and slingshot pressure keep you on the back foot. |
| Level 6 | Vayne | At 6 your Final Hour resets and Condemn spacing briefly let you reposition and reclaim the trade. |
| First item | Zac | On his first item Zac's HP stacking and blob sustain blunt your early true damage and out-sustain you. |
| Two+ items | Vayne | By 2+ items Vayne's stacked true damage and Condemn ignore his HP and win the 1v1. |
Level 1 is Vayne-favoured — Zac has no engage yet (E isn't up), so you can freely Q-auto him for Silver Bolts stacks and win the short trade before his blob sustain matters. Use this window: poke him off the wave and deny his passive blob pickups where you can. Once he hits 2-3 and gets E online, the lane shifts, so bank your early advantage.
The full Vayne vs Zac report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Zac vs Vayne guide →
All Vayne top lane matchups →