Cassiopeia vs Maokai — Top Lane Matchup Guide

How to win lane as Cassiopeia against Maokai · 58.33% win rate (48 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: Cassiopeia is favoured — 58.33% win rate over 48 games, and Cassiopeia's game plan below claims 6 of the 7 stage windows.

At a glance

Poison shreds HP stacking — free DPS lane where only his engage cooldown deserves respect.

Track: Maokai's W — Twisted Advance (14–10s cooldown). Point-and-click root — count its cooldown before stepping up.

Do

  • Tax every CS with Q poison
  • Take plates behind your DPS threat
  • Bank R for multi-man river stuns

Don't

  • Mana-dump E on a full-HP tank
  • Eat Twisted Advance (Root) for free in a farm lane
  • Stay top when your R wins fights elsewhere

Runes & build vs Maokai

Start
Doran's Ring + 2 Health Potions
First back
Oblivion Orb (≈800g) — cuts his healing
First item
Seraph's Embrace / Liandry's Torment
Then
Rylai's Crystal Scepter
Boots
No boots — bank the gold into MR via Rookern later
Runes
Conqueror (Precision): Presence of Mind, Legend: Haste, Last Stand · Sorcery: Manaflow Band, Transcendence · Shards: Adaptive Force, Adaptive Force, Health

Favour timeline — the windows in Cassiopeia's game plan

Read from Cassiopeia's seat: which stage windows this plan plays for against Maokai.

StageFavouredWhy
Level 1Even / skillYou have one ability and no poison stacking yet, while his Sapling-plus-Sap-Magic sustain trades you even — last-hit safely and don't step into Twisted Advance range.
Level 2CassiopeiaWith Q poison feeding Twin Fang's cooldown-and-mana refund, you out-DPS his auto-and-Sapling pokes the moment you can chain E.
Level 3CassiopeiaA full Q-to-E poison combo plus Serpentine Grace move speed wins any extended trade his immobile kit can't escape.
Levels 4-5CassiopeiaRanks in Q and E let you chain near-continuous Twin Fangs while W Miasma grounds his Twisted Advance — he cannot survive a committed trade.
Level 6CassiopeiaPetrifying Gaze stuns him the frame Twisted Advance lands — he is untargetable in transit, so wait for arrival, then chain E.
First itemCassiopeiaMalignance or early Liandry's plus your boots-free Serpentine Grace move speed lets you poke and shove him under tower with impunity.
Two+ itemsCassiopeiaYou still win the straight duel through his tankiness, but his real value is peel-tanking and rooting your carries — close the lane before fights decide the game.

How to beat Maokai as Cassiopeia: the early game

Maokai's only real threat early is Twisted Advance rooting you into a Bramble Smash knockback, so respect that one combo — if his W is up, poke at the edge of your Q range instead of walking into Advance range. His Saplings plus Sap Magic minion-heal just barely keep him even while you only have one ability online. The instant you have Q and E at 2-3, start priming him with Q poison and chaining Twin Fang resets; his sustain cannot out-heal your ramping poison once each tick refunds your E.

Hardest and easiest matchups for Cassiopeia in top lane

Pooled Emerald+ win rates from Cassiopeia's side, sampled July 2026.

Hardest

Easiest

Read the rest of this matchup

The full Cassiopeia vs Maokai report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Cassiopeia vs Maokai in top lane?

Cassiopeia — a 58.33% win rate vs Maokai in top lane over 48 games is a real advantage.

Is Cassiopeia vs Maokai a skill matchup?

Not really — Cassiopeia holds a real statistical advantage (58.33% win rate), so Maokai is the one working uphill.

Does Cassiopeia counter Maokai?

Statistically yes — Cassiopeia counters Maokai in top lane, winning 58.33% of 48 Emerald+ games.

What runes does Cassiopeia take vs Maokai?

Cassiopeia takes Conqueror on the Precision tree with Presence of Mind, Legend: Haste and Last Stand, and Sorcery secondary (Manaflow Band and Transcendence) vs Maokai.

What should Cassiopeia build vs Maokai?

Start Doran's Ring + 2 Health Potions and back for Oblivion Orb (≈800g) — cuts his healing. Build Seraph's Embrace / Liandry's Torment first, then Rylai's Crystal Scepter, with No boots — bank the gold into MR via Rookern later.

Related guides

Playing the other side? Maokai vs Cassiopeia guide →
All Cassiopeia top lane matchups →

More Cassiopeia top lane matchups: vs Locke · vs Lucian · vs Malphite · vs Master Yi · vs Mel · vs Mordekaiser