How to win lane as Cassiopeia against Locke · 45.97% win rate over 385 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Level 1 is even — his on-hit trades sting your squishy frame, but your Q poke makes his walk-up expensive; nobody trades for free. |
| Level 2 | Even / skill | Level 2 stays even: your E needs poison up before it pays, so trades stay short and honest on both sides. |
| Level 3 | Even / skill | Level 3 is a wash that revolves around your grounding W — land it on his approach and you win the exchange, miss and he closes for free. |
| Levels 4-5 | Even / skill | Levels 4-5 stay even — he hunts your W cooldown windows while you punish every approach with Q-into-E poison grinding. |
| Level 6 | Even / skill | Level 6 opens even: base ults and totems roughly trade, and your Gaze keeps his straightforward engages honest. |
| First item | Locke | First item is Locke's — a flanking E around your Gaze into Purgatory beats you. Ward the flanks, hug walls and never fight at execute-range health. |
| Two+ items | Even / skill | Late settles even as your ramping DPS meets his burst: he kills you through one clean pick, you melt him through one landed Gaze. |
An even but twitchy lane. His on-hit walk-ups sting your thin frame, so make him pay for every approach: Q on his path, then E him while poison ticks. Your E needs that poison setup, so don't spam it raw. From 3 on, drop W on the ground he must cross and farm the punishment.
The full Cassiopeia vs Locke report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Locke vs Cassiopeia guide →
All Cassiopeia top lane matchups →
Also played in: Mid Lane