Locke vs Cassiopeia — Top Lane Matchup Guide

How to win lane as Locke against Cassiopeia · 54.03% win rate over 385 Emerald+ games · Updated 2026-07-27

Verdict: Locke is favoured — Locke owns 1 of the 7 game windows. Locke wins 54.03% of games vs Cassiopeia in top lane (385 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Even / skillLevel 1 is even but your on-hit trade edges her thin frame.
Level 2Even / skillLevel 2 stays skill as her E needs a poison setup.
Level 3Even / skillLevel 3 is a wash around dodging her grounding W.
Levels 4-5Even / skillLevels 4-5 remain even as you punish her W cooldown.
Level 6Even / skillLevel 6 base is even until ults and totems trade.
First itemLockeLocke favoured — a flanking E plus R Purgatory beats her Gaze.
Two+ itemsEven / skillLate evens out as her ramping DPS meets your burst.

Early game (levels 1–5)

Levels 1-2 are even but you have the edge in a fight: Cassiopeia's Q pokes yet her E needs a poison target, so when her W is down you can E in and out-trade her thin HP with Ritual Nails.

Read the rest of this matchup

The full Locke vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Cassiopeia vs Locke guide →
All Locke top lane matchups →

Also played in: Mid Lane