Locke vs Cassiopeia — Top Lane Matchup Guide

How to win lane as Locke against Cassiopeia · 54.03% win rate (385 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: Locke is slightly favoured — 54.03% win rate over 385 games.

At a glance

A poke war you enter at 125 range — pay the toll early, then one blink turns her kite into a coffin the moment the nails land.

Track: Cassiopeia's W — Miasma (24–16s cooldown). Grounds you — dashes and leaps are disabled inside it.

Do

  • Bank W's refund for her poke rotation
  • Blink ONLY off a landed 2-3 stack nail string
  • R the retreat path, not the fight's start

Don't

  • Trade autos at her range for free
  • Burn E to farm what patience farms cheaper
  • Dive a full-HP kiter without the marks loaded

Runes & build vs Cassiopeia

Start
Doran's Ring + 2 Health Potions
First back
Oblivion Orb (≈800g) — sustain drags them back above your floor
First item
Lich Bane
Then
Shadowflame / Zhonya's (vs dive)
Boots
Mercury's Treads
Runes
Electrocute · Sudden Impact · Sixth Sense · Ultimate Hunter · Bone Plating · Second Wind

Favour timeline — the windows in Locke's game plan

Read from Locke's seat: which stage windows this plan plays for against Cassiopeia.

StageFavouredWhy
Level 1Even / skillLevel 1 is even but your on-hit trade edges her thin frame.
Level 2Even / skillLevel 2 stays skill as her E needs a poison setup.
Level 3Even / skillLevel 3 is a wash around dodging her grounding W.
Levels 4-5Even / skillLevels 4-5 remain even as you punish her W cooldown.
Level 6Even / skillLevel 6 base is even until ults and totems trade.
First itemLockeLocke favoured — a flanking E plus R Purgatory beats her Gaze.
Two+ itemsEven / skillLate evens out as her ramping DPS meets your burst.

How to beat Cassiopeia as Locke: the early game

Levels 1-2 are even but you have the edge in a fight: Cassiopeia's Q pokes yet her E needs a poison target, so in the 24s her W is down you can E in and out-trade her thin HP with Soul Nails.

Hardest and easiest matchups for Locke in top lane

Pooled Emerald+ win rates from Locke's side, sampled July 2026.

Hardest

Easiest

Read the rest of this matchup

The full Locke vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Locke vs Cassiopeia in top lane?

Locke, slightly — a 54.03% win rate edge over 385 games; execution can flip it.

Is Locke vs Cassiopeia a skill matchup?

Mostly — Locke has a small statistical edge (54.03% win rate), but execution decides this lane far more than the pick does.

Does Locke counter Cassiopeia?

Not a hard counter — Locke has a slight edge (54.03% win rate), and play quality decides the rest.

What runes does Locke take vs Cassiopeia?

Locke runs Electrocute · Sudden Impact · Sixth Sense · Ultimate Hunter · Bone Plating · Second Wind vs Cassiopeia.

What should Locke build vs Cassiopeia?

Start Doran's Ring + 2 Health Potions and back for Oblivion Orb (≈800g) — sustain drags them back above your floor. Build Lich Bane first, then Shadowflame / Zhonya's (vs dive), with Mercury's Treads.

Related guides

Playing the other side? Cassiopeia vs Locke guide →
All Locke top lane matchups →

More Locke top lane matchups: vs Ambessa · vs Aurora · vs Camille · vs Cho'Gath · vs Darius · vs Dr. Mundo

Also played in: Mid Lane