How to win lane as Locke against Cassiopeia · 50% win rate · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Level 1 is even with Cassiopeia mana-starved and both of you last-hitting. |
| Level 2 | Even / skill | Level 2 stays even as neither has a committal all-in yet. |
| Level 3 | Even / skill | At 3 it's a skill trade around her Q puddles and your poke. |
| Levels 4-5 | Even / skill | Levels 4-5 hold even as her E ramp balances your kill threat. |
| Level 6 | Locke | Level 6 favors you since your R kills while her ult misses if you angle it. |
| First item | Locke | First-item burst kills Cassiopeia before her sustained E comes online. |
| Two+ items | Even / skill | Two-plus items even it as her grounding and poison DPS win drawn-out fights. |
Levels 1-2 are even: Cassiopeia is slow and mana-starved early, so you can walk her down between Q puddles, but her passive movespeed means she kites once her poison is on you.
The full Locke vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
Become a Founding Member — $1.99/month →🔒 Secure checkout · 💰 7-day money-back guarantee · ✋ Cancel anytime
Early Access price — $3.99/month for new members after launch.
Playing the other side? Cassiopeia vs Locke guide →
All Locke mid lane matchups →
Also played in: Top Lane