Locke vs Cassiopeia — Mid Lane Matchup Guide

How to win lane as Locke against Cassiopeia · Matchup data reviewed on patch 26.15

Verdict: No Emerald+ win-rate sample for Locke vs Cassiopeia on this patch — play it as a skill matchup and win the windows in the plan below.

At a glance

A stationary spell-battery vs a blink with an execute — survive the poke tax pre-6, then every low-HP recall becomes a Purgatory receipt.

Track: Cassiopeia's W — Miasma (24–16s cooldown). Grounds you — dashes and leaps are disabled inside it.

Do

  • Stack nails on her every time she steps up to CS
  • Blink in only with 2-3 marks banked
  • R the moment she drops below a third — the totem finishes what your passive starts

Don't

  • Walk at her through open lane pre-6
  • Spend E to farm when she has prio
  • Trade while Miasma is up and your marks are zero

Runes & build vs Cassiopeia

Start
Doran's Ring + 2 Health Potions
First back
Oblivion Orb (≈800g) — cut the sustain before the execute war
First item
Lich Bane
Then
Shadowflame / Mejai's (if sealing)
Boots
Mercury's Treads / Sorcerer's Shoes
Runes
Electrocute · Sudden Impact · Sixth Sense · Ultimate Hunter · Bone Plating · Revitalize

Favour timeline — the windows in Locke's game plan

Read from Locke's seat: which stage windows this plan plays for against Cassiopeia.

StageFavouredWhy
Level 1Even / skillLevel 1 is even with Cassiopeia mana-starved and both of you last-hitting.
Level 2Even / skillLevel 2 stays even as neither has a committal all-in yet.
Level 3Even / skillAt 3 it's a skill trade around her Q puddles and your poke.
Levels 4-5Even / skillLevels 4-5 hold even as her E ramp balances your kill threat.
Level 6LockeLevel 6 favors you since your R kills while her ult misses if you angle it.
First itemEven / skillFirst-item burst kills Cassiopeia before her sustained E comes online.
Two+ itemsEven / skillTwo-plus items even it as her grounding and poison DPS win drawn-out fights.

How to beat Cassiopeia as Locke: the early game

Levels 1-2 are even: Cassiopeia is slow and mana-starved early, so you can walk her down between Q puddles, but her passive movespeed means she kites once her poison is on you. Even lane: Cassiopeia can't level her E early without gutting her poke, so trade when her Q puddle is on the ground already and step out of the lingering W grounding.

Read the rest of this matchup

The full Locke vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Locke vs Cassiopeia in mid lane?

No sample yet — Locke vs Cassiopeia has no Emerald+ win-rate data for this patch; treat it as a skill matchup and play the plan below.

What runes does Locke take vs Cassiopeia?

Locke runs Electrocute · Sudden Impact · Sixth Sense · Ultimate Hunter · Bone Plating · Revitalize vs Cassiopeia.

What should Locke build vs Cassiopeia?

Start Doran's Ring + 2 Health Potions and back for Oblivion Orb (≈800g) — cut the sustain before the execute war. Build Lich Bane first, then Shadowflame / Mejai's (if sealing), with Mercury's Treads / Sorcerer's Shoes.

Related guides

Playing the other side? Cassiopeia vs Locke guide →
All Locke mid lane matchups →

More Locke mid lane matchups: vs Aurora · vs Azir · vs Brand · vs Diana · vs Ekko · vs Fizz

Also played in: Top Lane