Maokai vs Cassiopeia — Top Lane Matchup Guide

How to win lane as Maokai against Cassiopeia · 48.84% win rate over 43 Emerald+ games · Updated 2026-07-27

Verdict: Cassiopeia is favoured — Cassiopeia owns 6 of the 7 game windows. Play it patient and win your windows. Maokai wins 48.84% of games vs Cassiopeia in top lane (43 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Even / skillYou have one ability and no combo at Level 1, but she has only a single poison tick too — last-hit at range, don't eat free Q (Noxious Blast), and set up your level-2 spike.
Level 2CassiopeiaShe gets her W (Miasma) grounding online and can drop it on your W (Twisted Advance) dash to cancel your only engage and start stacking poison.
Level 3CassiopeiaHer Q+W poison now out-ticks your Sap Magic heal across a full trade, so a clean W-root all-in no longer comes out ahead.
Levels 4-5CassiopeiaRepeated poke means her stacked poison damage beats your Passive sustain over the 4-5 window — every trade leaves you lower than her.
Level 6CassiopeiaHer R (Petrifying Gaze) face-stun stops your W-in cold, stunning you mid-engage and letting her kite the reset — your 6 doesn't answer hers.
First itemCassiopeiaHer first item (Liandry's/Malignance) plus boots-free move speed lets her stack poison faster than you heal and kite your step-up.
Two+ itemsCassiopeiaTwo items in she out-DPSes your full HP bar through your resistances and kites forever — you're a teamfight engage tool, not a duelist.

Early game (levels 1–5)

Levels 1-3 are your only real window, and even that is thin against her. At 2 your W (Twisted Advance) root into Q (Bramble Smash) is a hard trade she cannot match in melee, so step up the instant she walks forward to last-hit and proc Sap Magic off the all-in to heal the chip back. Do not face-tank her Q (Noxious Blast) poke for free — and watch her W (Miasma): if she drops that ground on you mid-dash it grounds you and cancels your W, so bait it or E (Sapling Toss) the spot first.

Read the rest of this matchup

The full Maokai vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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