Cassiopeia vs Camille — Top Lane Matchup Guide

How to win lane as Cassiopeia against Camille · 48.21% win rate (195 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: Camille is slightly favoured — Cassiopeia wins 48.21% of 195 games. Play it patient and win your windows.

At a glance

Miasma is the anti-dash button — ground her engage and the dive kit becomes a farm bot.

Track: Camille's E — Hookshot (16–12s cooldown). Her wall-dash stun — fight away from terrain while it is up.

Do

  • Hold W strictly for her dash window
  • Face the engage so R stuns, not slows
  • E-spam her while she's grounded

Don't

  • Waste Miasma on poke spacing
  • Get flanked with R already spent
  • Trade flat while Hookshot is loaded and W is down

Runes & build vs Camille

Start
Doran's Ring + 2 Health Potions
First back
Tear of the Goddess + Dark Seal (≈800g)
First item
Seraph's Embrace / Liandry's Torment
Then
Rylai's Crystal Scepter
Boots
No boots — bank the gold into Zhonya's earlier
Runes
Conqueror (Precision): Presence of Mind, Legend: Haste, Last Stand · Sorcery: Manaflow Band, Transcendence · Shards: Adaptive Force, Adaptive Force, Health

Favour timeline — the windows in Cassiopeia's game plan

Read from Cassiopeia's seat: which stage windows this plan plays for against Camille.

StageFavouredWhy
Level 1CassiopeiaLevel 1 we're both weak, but my Noxious Blast (Q) poison ticks on her last-hits and starts the DoT economy before she has a wall to Hookshot (E) off of.
Level 2Even / skillAt 2 my Miasma (W) comes online to ground her dash, but her empowered Precision Protocol (Q) keeps short trades even — neither of us fully commits yet.
Level 3CamilleWith her full combo she Hookshots (E) off a wall for the stun into Tactical Sweep's (W) outer-edge heal and an empowered true-damage Q, out-bursting your Twin Fang chain.
Levels 4-5CamilleRanks in Tactical Sweep (W) heal her through more of my chip than E-spam answers, and Miasma only buys time when it's off cooldown.
Level 6CamilleHextech Ultimatum (R) seals me into a 1v1 and walls off the minions, so my kited poison pattern collapses and my own R barely matters inside her box.
First itemEven / skillHer Tactical Sweep heal and item scaling keep the 2+ item duel a coin-flip — the lane stays hers until I can fight with my team instead of solo.
Two+ itemsCassiopeiaGrouped at 2+ items my Malignance/Liandry's plus Serpentine Grace speed let me Miasma-ground her dash and out-DPS her chained Twin Fang where she can't R-isolate me.

How to beat Camille as Cassiopeia: the early game

Level 1 is the one window I'm ahead — I drop Noxious Blast (Q) on the wave so it poisons her while she farms, starting the DoT economy before she has a wall to Hookshot (E) off of. But once Camille hits 3 this flips hard: she dashes in, second-casts E off a wall for the stun, lands the outer half of Tactical Sweep (W) for the bonus damage and a heal, then empowers her second Precision Protocol (Q) for true damage — and that front-loaded burst lands before my Twin Fang (E) chain ramps. Hookshot is 16s at rank 1 and my Miasma (W) ground only saves me if it's up, so I never waste it on the wave. Last-hit at Q range, eat the poke, and don't trade until all three of my abilities are ready.

Hardest and easiest matchups for Cassiopeia in top lane

Pooled Emerald+ win rates from Cassiopeia's side, sampled July 2026.

Hardest

Easiest

Read the rest of this matchup

The full Cassiopeia vs Camille report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Cassiopeia vs Camille in top lane?

Camille, slightly — Cassiopeia wins 48.21% of 195 games; winnable with the right plan.

Is Cassiopeia vs Camille a skill matchup?

Mostly — Camille has a small statistical edge (51.79% win rate), but execution decides this lane far more than the pick does.

Does Cassiopeia counter Camille?

No — if anything Camille has the slight edge (Cassiopeia wins 48.21%), though it stays close.

What runes does Cassiopeia take vs Camille?

Cassiopeia takes Conqueror on the Precision tree with Presence of Mind, Legend: Haste and Last Stand, and Sorcery secondary (Manaflow Band and Transcendence) vs Camille.

What should Cassiopeia build vs Camille?

Start Doran's Ring + 2 Health Potions and back for Tear of the Goddess + Dark Seal (≈800g). Build Seraph's Embrace / Liandry's Torment first, then Rylai's Crystal Scepter, with No boots — bank the gold into Zhonya's earlier.

Related guides

Playing the other side? Camille vs Cassiopeia guide →
All Cassiopeia top lane matchups →

More Cassiopeia top lane matchups: vs Akshan · vs Ambessa · vs Aurora · vs Cho'Gath · vs Darius · vs Dr. Mundo