Camille vs Cassiopeia — Top Lane Matchup Guide

How to win lane as Camille against Cassiopeia · 51.79% win rate (195 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: Camille is slightly favoured — 51.79% win rate over 195 games.

At a glance

Her W grounds your Hookshot — build MR, dodge Miasma, E only when it’s down.

Track: Cassiopeia's W — Miasma (24–16s cooldown). Grounds you — your Hookshot is disabled inside it. This is the whole matchup.

Do

  • Build MR
  • E-engage only when her W is down
  • Dodge her Q poke

Don't

  • E into her Miasma (you get grounded)
  • Poke-war from range
  • Fight her late scaling

Runes & build vs Cassiopeia

Start
Doran's Shield + Health Potion (vs her poke)
First back
Sheen + boots (≈1300g) — Q-reset spike
First item
Trinity Force (Sheen → lethal Q resets)
Then
Sundered Sky
Boots
Mercury's Treads
Runes
Conqueror (Precision): Triumph, Legend: Alacrity, Last Stand · Resolve: Second Wind, Bone Plating · Shards: Adaptive Force, Adaptive Force, Magic Resist

Favour timeline — the windows in Camille's game plan

Read from Camille's seat: which stage windows this plan plays for against Cassiopeia.

StageFavouredWhy
Level 1CassiopeiaNoxious Blast (Q) out-ranges your single level-1 ability and gives her move speed to disengage — you have no all-in tool yet and just eat free poke.
Level 2Even / skillYou get Q rank-2 but it's still even — her ramping poison and Twin Fang DPS trade with your developing kit until your W is also online.
Level 3CamilleYour Q re-cast true damage plus W's outer-edge max-HP slash and self-heal win every short trade before her Twin Fang poison-DPS can stack up.
Levels 4-5CamilleYou out-trade a pre-item Cass: E in, W the edge, double-Q, and her lack of any dash means she can't escape your follow-up stun.
Level 6CamilleHextech Ultimatum isolates her into an arena where her kiting and passive move speed are dead, and angling your leap dodges her Petrifying Gaze cone to win the all-in.
First itemEven / skillYour first bruiser item keeps tempo even with her first AP item — force the all-in before her second component lands and her Twin Fang DPS spikes.
Two+ itemsCassiopeiaShe hard-scales: full-build Cass grounds your E re-cast with Miasma and chain-casts Twin Fang from range to poison-kite the duel back completely.

How to beat Cassiopeia as Camille: the early game

Level 1-2 is hers — Noxious Blast (Q) out-ranges your single ability and hands her move speed to disengage, so don't walk up for a cs into her poke. Farm with Precision Protocol last-hits and let your passive Adaptive Defenses shield soak a poison tick on the rare step-in. Don't trade until you have Q rank-2 and a point in W, or you just feed her free poison stacks and her Twin Fang (E) ramp for nothing.

Hardest and easiest matchups for Camille in top lane

Pooled Emerald+ win rates from Camille's side, sampled July 2026.

Hardest

Easiest

Read the rest of this matchup

The full Camille vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Camille vs Cassiopeia in top lane?

Camille, slightly — a 51.79% win rate edge over 195 games; execution can flip it.

Is Camille vs Cassiopeia a skill matchup?

Mostly — Camille has a small statistical edge (51.79% win rate), but execution decides this lane far more than the pick does.

Does Camille counter Cassiopeia?

Not a hard counter — Camille has a slight edge (51.79% win rate), and play quality decides the rest.

What runes does Camille take vs Cassiopeia?

Camille takes Conqueror on the Precision tree with Triumph, Legend: Alacrity and Last Stand, and Resolve secondary (Second Wind and Bone Plating) vs Cassiopeia.

What should Camille build vs Cassiopeia?

Start Doran's Shield + Health Potion (vs her poke) and back for Sheen + boots (≈1300g) — Q-reset spike. Build Trinity Force (Sheen → lethal Q resets) first, then Sundered Sky, with Mercury's Treads.

Related guides

Playing the other side? Cassiopeia vs Camille guide →
All Camille top lane matchups →

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