Yasuo vs Cassiopeia — Mid Lane Matchup Guide

How to win lane as Yasuo against Cassiopeia · 53.06% win rate over 1,355 Emerald+ games · Updated 2026-07-27

Verdict: Winnable despite the lane — Cassiopeia owns 4 of the 7 game windows to Yasuo's 1, yet the win rate favours Yasuo: survive their windows and the game is yours. Yasuo wins 53.06% of games vs Cassiopeia in mid lane (1,355 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Even / skillEven L1: neither wins, Cass lacks damage and you lack a target to dash to.
Level 2Even / skillEven L2: still a skill lane with weak Cass combo and cautious Yasuo farming.
Level 3CassiopeiaCass favours L3: Miasma grounds your E and Twin Fang out-sustains your trades.
Levels 4-5CassiopeiaCass favours L4-5: her grounding plus poke zones you off the wave repeatedly.
Level 6CassiopeiaCass favours L6: Petrifying Gaze stuns your dash and you cannot Wind Wall the cone.
First itemCassiopeiaCass favours 1st item: her Twin Fang healing on early AP outpaces your chip damage.
Two+ itemsYasuoYou favour 2+ items: your knockup-R burst finally beats her sustain and Wind Wall blocks her Q.

Early game (levels 1–5)

The first two levels are a skill lane: Cass has weak base damage before her combo comes online, so you contest Q pokes and last-hits evenly.

Read the rest of this matchup

The full Yasuo vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Cassiopeia vs Yasuo guide →
All Yasuo mid lane matchups →

Also played in: Top Lane