Vladimir vs Ryze — Mid Lane Matchup Guide

How to win lane as Vladimir against Ryze · 53.81% win rate over 1,918 Emerald+ games · Updated 2026-07-27

Verdict: Vladimir is favoured — Vladimir owns 4 of the 7 game windows to Ryze's 3. Vladimir wins 53.81% of games vs Ryze in mid lane (1,918 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1RyzeRyze's Overload outranges your Transfusion and pokes you at level 1.
Level 2RyzeAt 2 his Rune Prison root sets up trades your heal can't win.
Level 3RyzeLevel 3 his full Q-W-E combo chunks you harder than you sustain back.
Levels 4-5VladimirBy 4-5 your Tides of Blood sustain finally outheals his poke output.
Level 6VladimirLevel 6 Realm Warp is pure utility, so your all-in wins the fight.
First itemVladimirYour first item's drain outlasts his mana-limited poke completely.
Two+ itemsVladimirAt two items your Hemoplague teamfight and Pool immunity outscale Ryze.

Early game (levels 1–5)

Ryze wins levels 1-3: his Overload out-ranges Transfusion and his root-into-poke combo chunks you every time you step up to CS, so play safe and take the wave passively.

Read the rest of this matchup

The full Vladimir vs Ryze report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Ryze vs Vladimir guide →
All Vladimir mid lane matchups →

Also played in: Top Lane