How to win lane as Ryze against Vladimir · 47.33% win rate (3,839 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15
He out-ranges your combo for five levels — farm the Tear, dodge the big spell, and let the item curve flip the lane.
Track: Vladimir's W — Sanguine Pool (28–16s cooldown). Untargetable dodge — bait it before you spend your kill window.
Read from Ryze's seat: which stage windows this plan plays for against Vladimir.
This is Ryze's own plan; across 3,839 pooled games the lane is leaning Vladimir.
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Ryze | Ryze favored: Vladimir is weak and mana-starved at level 1 while you can trade freely. |
| Level 2 | Ryze | Ryze favored: at level 2 you out-trade him before his Transfusion cooldown is short. |
| Level 3 | Ryze | Ryze favored: at level 3 your W root and Q-E-Q chunk him whenever his Q is down. |
| Levels 4-5 | Even / skill | Skill: at 4-5 his sustain starts coming online and trades even out. |
| Level 6 | Vladimir | Vladimir favored: Hemoplague (R) and Sanguine Pool (W) let him dodge and heal through your all-in. |
| First item | Even / skill | Ryze favored: your first item's Tear-stacked DPS out-paces his healing in short trades. |
| Two+ items | Vladimir | Vladimir favored: with 2+ items his health stacking and R amp out-sustain you in any duel. |
Levels 1-3 are firmly yours: Vladimir is mana-starved and weak before he scales, so W root him and Q-E-Q every time his Transfusion (Q) is on cooldown to build an early lead. Track Sanguine Pool: 28s at rank 1, 16s max — untargetable for 2s; bait it and his kill window is yours for most of half a minute. E unlocks the real combo: E-Q flux chunks and the wave-bounce clears. The lane starts being yours to play.
Pooled Emerald+ win rates from Ryze's side, sampled July 2026.
The full Ryze vs Vladimir report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
Read the full guide — plans from $1.99/month →🔒 Secure checkout · 💰 7-day money-back guarantee on your first payment · ✋ Cancel anytime
Lane Pass $1.99/mo · All Lanes $3.99/mo · Annual $24.99/yr. Renews automatically — cancel anytime.
Vladimir, slightly — Ryze wins 47.33% of 3,839 games; winnable with the right plan.
Mostly — Vladimir has a small statistical edge (52.67% win rate), but execution decides this lane far more than the pick does.
No — if anything Vladimir has the slight edge (Ryze wins 47.33%), though it stays close.
Ryze takes Phase Rush on the Sorcery tree with Manaflow Band, Transcendence and Scorch, and Inspiration secondary (Biscuit Delivery and Cosmic Insight) vs Vladimir.
Start Doran's Ring + 2 Health Potions and back for Oblivion Orb (≈800g) — cuts his sustain. Build Rod of Ages first, then Seraph's Embrace, with Sorcerer's Shoes / Mercury's Treads.
Playing the other side? Vladimir vs Ryze guide →
All Ryze mid lane matchups →
More Ryze mid lane matchups: vs Veigar · vs Vex · vs Viktor · vs Xerath · vs Yasuo · vs Yone
Also played in: Top Lane