Ryze vs Vladimir — Mid Lane Matchup Guide

How to win lane as Ryze against Vladimir · 48.46% win rate over 1,921 Emerald+ games · Updated 2026-07-27

Verdict: Closer than it looks — Ryze owns 4 of the 7 game windows to Vladimir's 2, but the win rate still favours Vladimir: you have to convert those windows or the game slips away. Ryze wins 48.46% of games vs Vladimir in mid lane (1,921 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1RyzeRyze favored: Vladimir is weak and mana-starved at level 1 while you can trade freely.
Level 2RyzeRyze favored: at level 2 you out-trade him before his Transfusion cooldown is short.
Level 3RyzeRyze favored: at level 3 your W root and Q-E-Q chunk him whenever his Q is down.
Levels 4-5Even / skillSkill: at 4-5 his sustain starts coming online and trades even out.
Level 6VladimirVladimir favored: Hemoplague (R) and Sanguine Pool (W) let him dodge and heal through your all-in.
First itemRyzeRyze favored: your first item's Tear-stacked DPS out-paces his healing in short trades.
Two+ itemsVladimirVladimir favored: with 2+ items his health stacking and R amp out-sustain you in any duel.

Early game (levels 1–5)

Levels 1-3 are firmly yours: Vladimir is mana-starved and weak before he scales, so W root him and Q-E-Q every time his Transfusion (Q) is on cooldown to build an early lead.

Read the rest of this matchup

The full Ryze vs Vladimir report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Vladimir vs Ryze guide →
All Ryze mid lane matchups →

Also played in: Top Lane