How to win lane as Ryze against Annie · 43.95% win rate over 860 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Annie | Level 1 Annie's point-and-click Q and stun buildup give her uncontested poke. |
| Level 2 | Annie | Level 2 a charged Pyromania stun threatens burst you cannot dodge at short range. |
| Level 3 | Annie | Level 3 her stun-into-Q combo remains a kill threat you can only respect. |
| Levels 4-5 | Annie | Levels 4-5 a full stun still deletes you before your kit can respond. |
| Level 6 | Annie | Level 6 Summon: Tibbers on a stun is a guaranteed one-combo kill. |
| First item | Ryze | First item health lets you survive Tibbers and punish her long cooldown. |
| Two+ items | Ryze | Two-plus items your sustained Q DPS and R dominate her one-note burst kit. |
Levels 1-2 are all Annie: her point-and-click Q Disintegrate and building Pyromania stun let her poke and threaten a stun-burst you can't dodge, so last-hit at max range and watch her passive stack count religiously.
The full Ryze vs Annie report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Annie vs Ryze guide →
All Ryze mid lane matchups →