Vladimir vs Pantheon — Mid Lane Matchup Guide

How to win lane as Vladimir against Pantheon · 54.39% win rate over 1,993 Emerald+ games · Updated 2026-07-27

Verdict: Winnable despite the lane — Pantheon owns 5 of the 7 game windows to Vladimir's 2, yet the win rate favours Vladimir: survive their windows and the game is yours. Vladimir wins 54.39% of games vs Pantheon in mid lane (1,993 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1PantheonPantheon's Comet Spear outranges Transfusion and pokes you off the wave at level 1.
Level 2PantheonAt 2 his Aegis Assault and empowered Q win every short trade you attempt.
Level 3PantheonLevel 3 Shield Vault gives him a point-blank stun all-in you can't Pool through.
Levels 4-5VladimirBy 4-5 your Tides of Blood sustain lets you outheal his poke and stabilize.
Level 6PantheonLevel 6 Grand Starfall hands him roam and dive pressure that beats your combo.
First itemPantheonHis committed all-in still overpowers you until your first item's sustain lands.
Two+ itemsVladimirAt two items your Hemoplague teamfight and Pool immunity outscale his falloff.

Early game (levels 1–5)

Pantheon controls levels 1-3: his Comet Spear outranges your Transfusion and his Shield Vault beats any melee trade, so farm with Q and don't walk up into E range.

Read the rest of this matchup

The full Vladimir vs Pantheon report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Pantheon vs Vladimir guide →
All Vladimir mid lane matchups →

Also played in: Top Lane