How to win lane as Pantheon against Vladimir · 52.34% win rate over 428 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Pantheon | Level 1 favours you: Vlad has no escape and Transfusion costs him HP, so your base damage wins trades outright. |
| Level 2 | Pantheon | Level 2 favours you: your W stun and second ability let you punish his escape-less, poke-vulnerable early game. |
| Level 3 | Pantheon | Level 3 favours you: full combo point-blank chunks him while Sanguine Pool is his only long-cooldown out. |
| Levels 4-5 | Pantheon | Levels 4-5 favour you: you can bait the pool and all-in repeatedly before any HP-AP stacking matters. |
| Level 6 | Pantheon | Level 6 favours you: your Grand Starfall all-in beats his teamfight-oriented Hemoplague this early. |
| First item | Pantheon | First item favours you: your Eclipse/Trinity burst still kills him if you commit before he pools out. |
| Two+ items | Vladimir | Two-plus items favour Vladimir: HP-AP stacking, pool immunity, and Hemoplague let him heal through your entire combo. |
Levels 1-2 are yours: Vlad has no early escape until Sanguine Pool, his Transfusion costs HP, and your base damage plus W stun win every trade. Poke him whenever he steps to last-hit and push so he can't farm safely.
The full Pantheon vs Vladimir report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Vladimir vs Pantheon guide →
All Pantheon mid lane matchups →
Also played in: Top Lane