Pantheon vs Vladimir — Mid Lane Matchup Guide

How to win lane as Pantheon against Vladimir · 46.8% win rate (2,421 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15

Verdict: A close lane that leans Vladimir on paper (Pantheon wins 46.8%), but Pantheon's plan below claims 3 of the 7 windows: convert them and the stats catch up to you.

At a glance

He scales and you collect early — spear every contact, stun the level-2 window, and convert before his items file an appeal.

Track: Vladimir's W — Sanguine Pool (28–16s cooldown). Untargetable dodge — bait it before you spend your kill window.

Do

  • Spear every last-hit attempt
  • Cash the level 2 stun window
  • Convert leads to plates before two items

Don't

  • Coast at even farm — you LOSE even
  • Hold the empowered spear for perfect moments
  • Trade at his range after his first item

Runes & build vs Vladimir

Start
Doran's Blade + Health Potion
First back
Executioner's Calling (≈800g) — cuts his sustain
First item
Eclipse
Then
Serylda's / Sterak's path
Boots
Mercury's Treads / Lucidity
Runes
Conqueror (Precision): Triumph, Legend: Alacrity, Coup de Grace · Inspiration: Biscuit Delivery, Cosmic Insight · Shards: Adaptive Force, Adaptive Force, Health

Favour timeline — the windows in Pantheon's game plan

Read from Pantheon's seat: which stage windows this plan plays for against Vladimir.

This is Pantheon's own plan; across 2,421 pooled games the lane is leaning Vladimir.

StageFavouredWhy
Level 1PantheonLevel 1 favours you: Vlad has no escape and Transfusion costs him HP, so your base damage wins trades outright.
Level 2PantheonLevel 2 favours you: your W stun and second ability let you punish his escape-less, poke-vulnerable early game.
Level 3PantheonLevel 3 favours you: full combo point-blank chunks him while Sanguine Pool is his only long-cooldown out.
Levels 4-5Even / skillLevels 4-5: you can bait the pool and all-in repeatedly before any HP-AP stacking matters.
Level 6Even / skillLevel 6: your Grand Starfall all-in beats his teamfight-oriented Hemoplague this early.
First itemEven / skillFirst item: your Eclipse/Trinity burst still kills him if you commit before he pools out.
Two+ itemsVladimirTwo-plus items favour Vladimir: HP-AP stacking, pool immunity, and Hemoplague let him heal through your entire combo.

How to beat Vladimir as Pantheon: the early game

Levels 1-2 are yours: Vlad has no early escape until Sanguine Pool, his Transfusion costs HP, and your base damage plus W stun win every trade. Poke him whenever he steps to last-hit and push so he can't farm safely. Track Vladimir Sanguine Pool: matchup-defining — Untargetable dodge on a 28s cooldown — bait it before you spend your kill window. Check it before every step-up.

Hardest and easiest matchups for Pantheon in mid lane

Pooled Emerald+ win rates from Pantheon's side, sampled July 2026.

Hardest

Easiest

Read the rest of this matchup

The full Pantheon vs Vladimir report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Common questions

Who wins Pantheon vs Vladimir in mid lane?

Vladimir, slightly — Pantheon wins 46.8% of 2,421 games; winnable with the right plan.

Is Pantheon vs Vladimir a skill matchup?

Mostly — Vladimir has a small statistical edge (53.2% win rate), but execution decides this lane far more than the pick does.

Does Pantheon counter Vladimir?

No — if anything Vladimir has the slight edge (Pantheon wins 46.8%), though it stays close.

What runes does Pantheon take vs Vladimir?

Pantheon takes Conqueror on the Precision tree with Triumph, Legend: Alacrity and Coup de Grace, and Inspiration secondary (Biscuit Delivery and Cosmic Insight) vs Vladimir.

What should Pantheon build vs Vladimir?

Start Doran's Blade + Health Potion and back for Executioner's Calling (≈800g) — cuts his sustain. Build Eclipse first, then Serylda's / Sterak's path, with Mercury's Treads / Lucidity.

Related guides

Playing the other side? Vladimir vs Pantheon guide →
All Pantheon mid lane matchups →

More Pantheon mid lane matchups: vs Veigar · vs Vex · vs Viktor · vs Xerath · vs Yasuo · vs Yone

Also played in: Top Lane