Vex vs Neeko — Mid Lane Matchup Guide

How to win lane as Vex against Neeko · 54.06% win rate over 677 Emerald+ games · Updated 2026-07-27

Verdict: Vex is favoured — Vex owns 7 of the 7 game windows. Vex wins 54.06% of games vs Neeko in mid lane (677 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1VexLevel 1 favours Vex since point-click Gloom beats her skillshot poke.
Level 2VexLevel 2 stays Vex-favoured as you chip her while she stacks safely.
Level 3VexLevel 3 favours Vex with Gloom-Q out-ranging Blooming Burst trades.
Levels 4-5VexLevels 4-5 favour Vex as primed Fear cancels her E root setups.
Level 6VexLevel 6 is Vex-favoured because R and Fear interrupt Pop Blossom cleanly.
First itemVexFirst item favours Vex since Fear burst kills her before her R detonates.
Two+ itemsVex2+ items is Vex-favoured as you one-shot an immobile Neeko from range.

Early game (levels 1–5)

Levels 1-2 favour you: your point-click Gloom poke chips Neeko while she has to land skillshot Blooming Burst (Q), so build passive stacks and respect only her Tangle-Barbs (E).

Read the rest of this matchup

The full Vex vs Neeko report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Neeko vs Vex guide →
All Vex mid lane matchups →