Vex vs Vladimir — Mid Lane Matchup Guide

How to win lane as Vex against Vladimir · 48.72% win rate over 1,599 Emerald+ games · Updated 2026-07-27

Verdict: Closer than it looks — Vex owns 7 of the 7 game windows, but the win rate still favours Vladimir: you have to convert those windows or the game slips away. Vex wins 48.72% of games vs Vladimir in mid lane (1,599 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1VexYou dominate level 1 — his sustain is on cooldown and E costs him health to poke.
Level 2VexCharged Q punishes his weak early trades and denies his farm at level 2.
Level 3VexAt 3 you out-trade him before his Transfusion sustain comes online.
Levels 4-5VexLevels 4-5 you keep shoving and winning trades while he's forced to bleed health.
Level 6VexShadow Surge lets you all-in once you bait his Sanguine Pool escape.
First itemVexOne item chunks him past his sustain when you land E-Q on a Gloom target.
Two+ itemsVexLate your pick pressure and roams close the game before his Hemoplague scaling wins fights.

Early game (levels 1–5)

Levels 1-2 you dominate: his Transfusion cooldown is long and E costs health, so poke him with charged Q and force him to bleed CS he can't recover.

Read the rest of this matchup

The full Vex vs Vladimir report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Vladimir vs Vex guide →
All Vex mid lane matchups →