How to win lane as Vex against Vladimir · 47.02% win rate (3,222 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15
An even poke war where his mobility advantage doesn't exist — trade marked rotations and let Gloom math grind the margins.
Track: Vladimir's W — Sanguine Pool (28–16s cooldown). Untargetable dodge — bait it before you spend your kill window.
Read from Vex's seat: which stage windows this plan plays for against Vladimir.
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | His sustain is on cooldown and E costs him health to poke. |
| Level 2 | Even / skill | Charged Q punishes his weak early trades and denies his farm at level 2. |
| Level 3 | Even / skill | At 3 you out-trade him before his Transfusion sustain comes online. |
| Levels 4-5 | Even / skill | Levels 4-5 you keep shoving and winning trades while he's forced to bleed health. |
| Level 6 | Even / skill | Shadow Surge lets you all-in once you bait his Sanguine Pool escape. |
| First item | Even / skill | One item chunks him past his sustain when you land E-Q on a Gloom target. |
| Two+ items | Even / skill | Late your pick pressure and roams close the game before his Hemoplague scaling wins fights. |
Levels 1-2 you dominate: his Transfusion cooldown is long and E costs health, so poke him with charged Q and force him to bleed CS he can't recover. Track Vladimir Sanguine Pool: matchup-defining, 28s at rank 1 falling to 16 — bait it before you spend your kill window. Vladimir is at his weakest here: his Transfusion (Q) sustain is on a long cooldown early and Tides of Blood (E) costs health to charge. Out-poke him with charged Q every time he steps to farm, and force him to spend health he can't yet recover.
Pooled Emerald+ win rates from Vex's side, sampled July 2026.
The full Vex vs Vladimir report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Vladimir, slightly — Vex wins 47.02% of 3,222 games; winnable with the right plan.
Mostly — Vladimir has a small statistical edge (52.98% win rate), but execution decides this lane far more than the pick does.
No — if anything Vladimir has the slight edge (Vex wins 47.02%), though it stays close.
Vex takes Electrocute on the Domination tree with Cheap Shot, Grisly Mementos and Ultimate Hunter, and Sorcery secondary (Manaflow Band and Transcendence) vs Vladimir.
Start Doran's Ring + 2 Health Potions and back for Oblivion Orb (≈800g) — cuts his sustain. Build Luden's Companion first, then Shadowflame, with Sorcerer's Shoes / Mercury's Treads.
Playing the other side? Vladimir vs Vex guide →
All Vex mid lane matchups →
More Vex mid lane matchups: vs Twisted Fate · vs Veigar · vs Viktor · vs Xerath · vs Yasuo · vs Yone