Annie vs Vex — Mid Lane Matchup Guide

How to win lane as Annie against Vex · 57.56% win rate over 714 Emerald+ games · Updated 2026-07-27

Verdict: Annie is favoured — Annie owns 3 of the 7 game windows to Vex's 1. Annie wins 57.56% of games vs Vex in mid lane (714 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1Even / skillLevels 1-2 are an even skill matchup with both champions relying on landed pokes, no clear damage edge
Level 2Even / skillLevel 2 stays even — same skillshot-trading logic applies
Level 3Even / skillLevel 3 remains a skill check as stun/fear windows are roughly symmetric
Levels 4-5AnnieAnnie's reliable stun-into-Tibbers setup starts to edge past Vex's poke pattern by mid lane
Level 6AnnieTibbers at 6 lets Annie force a favorable all-in that Vex's fear-on-dash ult doesn't answer
First itemAnnieAnnie's first-item burst kills Vex before her Gloom stacks come online
Two+ itemsVexVex's late-game Gloom/Doombringer burst scaling overtakes Annie's damage once she has a full mage item

Early game (levels 1–5)

Levels 1-2 are an even poke war between two skillshot/CC casters — whoever lands Mistral Bolt or your Q first wins the exchange, with no inherent damage lead either way.

Read the rest of this matchup

The full Annie vs Vex report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Vex vs Annie guide →
All Annie mid lane matchups →