How to win lane as Vayne against Gwen · 55.82% win rate over 335 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Vayne | Vayne pokes freely with Silver Bolts and Tumble autos while Gwen must walk up to melee-farm. |
| Level 2 | Vayne | Vayne keeps chipping Gwen at Level 2 before Snip Snip becomes a real threat. |
| Level 3 | Vayne | Vayne still controls Level 3 by punishing walk-ups and Condemning Gwen's Skip 'n Slash engages. |
| Levels 4-5 | Vayne | Through Levels 4-5 Vayne's range and Condemn keep her ahead of Gwen's short-cooldown dashes. |
| Level 6 | Gwen | At Level 6 Needle Work plus Hallowed Mist make Gwen untargetable and let her all-in through Vayne's kite. |
| First item | Gwen | Gwen's Mist, sustain, and R execute out-scale Vayne's early lead once her items come online. |
| Two+ items | Even / skill | Late it's even skill — Vayne's %-health DPS and Final Hour kiting trade against Gwen's Mist untargetability. |
You win Levels 1-2 clean — Gwen must melee-auto to farm while your Silver Bolts and max-range Tumble autos chip her freely, and her Snip Snip (Q) isn't a threat yet. Poke every last-hit.
The full Vayne vs Gwen report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Gwen vs Vayne guide →
All Vayne top lane matchups →