How to win lane as Mordekaiser against Vayne · 50.1% win rate (1,443 Emerald+ games, lolalytics, sampled July 2026) · Matchup data reviewed on patch 26.15
Her condemn and %-true kite your immobile kit all game. Build MR, freeze the wave, and gank-pressure her.
Track: Vayne's E — Condemn (20–12s cooldown). Wall-stun. R her so she can’t kite.
Read from Mordekaiser's seat: which stage windows this plan plays for against Vayne.
This is Mordekaiser's own plan; across 1,443 pooled games the lane is even.
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Even / skill | Neither has an all-in at level 1 — she can only poke at range and you have no Darkness Rise aura stacked yet, so just farm and set up your level 2 spike. |
| Level 2 | Mordekaiser | Q + W online: single-target Obliterate poke and W shield sustain out-trade her low early autos before she owns a crit item to kite with. |
| Level 3 | Mordekaiser | With Q, W and E started your trades grind her down — land E on a tumble and your Darkness Rise aura punishes any extended fight she takes. |
| Levels 4-5 | Mordekaiser | Levels 4-5 are still yours: Q ranks make isolated Obliterate huge, Death's Grasp yanks her out of a Tumble, and Darkness Rise punishes any extended fight she misjudges in melee. |
| Level 6 | Mordekaiser | Realm of Death is the cliff: it reaches 650 so you ult from outside her 550 Condemn, there is no wall to stun you inside, no team to peel, and you keep her stats. |
| First item | Vayne | Her first crit item is where it turns: Silver Bolts' third-hit percent-max-HP true damage walks through your W shield and every resist you bought, and your Obliterate is too slow to answer it. |
| Two+ items | Vayne | She out-scales hard late: percent-HP true damage shreds your tankiness, Condemn punishes facechecks, and she kites your slow telegraphed Q all day — play the pick, not the chase. |
"At level 1 you both just farm — neither has a real all-in, so soak the wave and don't chase a tumble you can't catch with no aura up yet. Your spike is level 2-3: once Q Obliterate and W Indestructible are online, your single-target poke plus banked shield out-trade her short early autos, and she has no crit item yet to kite you safely. Punch in when she steps up to last-hit, land Q for the single-target bonus and a Darkness Rise stack, and bank W damage so a returned Silver Bolts proc just refills your heal. Save E to yank her if she tumbles toward you."
Pooled Emerald+ win rates from Mordekaiser's side, sampled July 2026.
The full Mordekaiser vs Vayne report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Nobody on paper — a 50.1% win rate over 1,443 games makes this a coin flip decided by play, not champion select.
Yes — Mordekaiser vs Vayne is a genuine skill matchup: 50.1% win rate, and the favour swings window to window rather than being set at champion select.
No hard counter either way — the Mordekaiser vs Vayne win rate is 50.1%, an even lane decided by execution.
Mordekaiser takes Conqueror on the Precision tree with Triumph, Legend: Haste and Last Stand, and Resolve secondary (Second Wind and Overgrowth) vs Vayne.
Start Doran's Shield + Health Potion and back for Haunting Guise / Giant's Belt (≈900-1300g). Build Liandry's Torment (burn carries her extended trades) first, then Riftmaker (omnivamp turns the Realm 1v1 unloseable), with Plated Steelcaps (Swiftness into kite comps).
Playing the other side? Vayne vs Mordekaiser guide →
All Mordekaiser top lane matchups →
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