How to win lane as Vex against Cassiopeia · 58.13% win rate over 406 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Vex | At level 1 you out-range Cass, who leans on Q mainly for movement, so you win the poke. |
| Level 2 | Vex | At 2 your empowered Q and W burst beat her before Miasma and E-sustain exist. |
| Level 3 | Vex | By 3 you still dictate range and punish her short Noxious Blast walk-ups. |
| Levels 4-5 | Cassiopeia | At 4-5 her Miasma grounds you and Twin Fang sustain flips extended trades to Cass. |
| Level 6 | Vex | Your level 6 R is a hard pick on a dash-less target, swinging the ult window back to you. |
| First item | Cassiopeia | Her first-item tear spike makes Twin Fang out-DPS you in any grounded fight, favouring Cass. |
| Two+ items | Vex | Two items in your R burst and shield delete her before Twin Fang ramps, restoring your edge. |
You have the range and burst edge at levels 1-3 — she's stuck using Q (Noxious Blast) mostly for movespeed and can't punch back, so land empowered Q and W poke before her kit comes online.
The full Vex vs Cassiopeia report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Cassiopeia vs Vex guide →
All Vex mid lane matchups →