How to win lane as Twisted Fate against Vex · 54.12% win rate over 1,565 Emerald+ games · Updated 2026-07-27
| Stage | Favoured | Why |
|---|---|---|
| Level 1 | Vex | At 1 Vex's Mistral Bolt poke and shield-break passive punish your dash-less start. |
| Level 2 | Twisted Fate | At 2 your Blue Card poke and Wild Cards shove let you seize lane tempo. |
| Level 3 | Even / skill | Level 3 is skill-based as both of you trade poke without a committed all-in. |
| Levels 4-5 | Even / skill | Levels 4-5 stay even with shoves and dodges deciding each short trade. |
| Level 6 | Vex | At 6 her global Shadow Surge and Gloom burst edge your duel in lane. |
| First item | Twisted Fate | With first item your Destiny roams and Gold Card picks out-tempo her single engage. |
| Two+ items | Vex | By 2+ items her AoE fear R and marked burst make her the better teamfighter. |
Vex edges level 1 with Mistral Bolt poke and passive shield-break against your immobile laning, so play back and last-hit carefully until you have a stun.
The full Twisted Fate vs Vex report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.
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Playing the other side? Vex vs Twisted Fate guide →
All Twisted Fate mid lane matchups →