Twisted Fate vs Annie — Mid Lane Matchup Guide

How to win lane as Twisted Fate against Annie · 50.55% win rate over 1,274 Emerald+ games · Updated 2026-07-27

Verdict: Winnable despite the lane — Annie owns 5 of the 7 game windows to Twisted Fate's 1, yet the win rate favours Twisted Fate: survive their windows and the game is yours. Twisted Fate wins 50.55% of games vs Annie in mid lane (1,274 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1AnnieLevel 1 goes to Annie because her stun-burst threat dominates your fragile early autos.
Level 2AnnieLevel 2 stays Annie as her Pyromania stacks enable a guaranteed stun trade.
Level 3AnnieLevel 3 remains Annie with her full Q-W-stun combo online.
Levels 4-5AnnieLevels 4-5 stay Annie because her repeatable stun all-in outclasses your kit.
Level 6AnnieLevel 6 favours Annie because Flash-Tibbers with a full stun bar deletes you.
First itemTwisted FateAt first item you take over as Rod of Ages and Destiny roams outpace her short range.
Two+ itemsEven / skillWith two items it evens out between her teamfight ult and your pick-and-vision control.

Early game (levels 1–5)

Levels 1 through 5 all belong to Annie: her Disintegrate stun and Pyromania passive give her a repeatable guaranteed-stun burst combo that your weak early autos and unreliable Pick a Card simply can't contest, so play safe and farm at range.

Read the rest of this matchup

The full Twisted Fate vs Annie report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Playing the other side? Annie vs Twisted Fate guide →
All Twisted Fate mid lane matchups →