Qiyana vs Annie — Mid Lane Matchup Guide

How to win lane as Qiyana against Annie · 53.04% win rate over 526 Emerald+ games · Updated 2026-07-27

Verdict: Qiyana is favoured — Qiyana owns 6 of the 7 game windows to Annie's 1. Qiyana wins 53.04% of games vs Annie in mid lane (526 Emerald+ games analysed).

Favour timeline — who owns each window

StageFavouredWhy
Level 1AnnieLevel 1 is Annie's — her point-and-click Q pokes and stacks Pyromania while you have no element to answer.
Level 2QiyanaLevel 2 flips to you: an attuned element gives your combo and she has no mobility to escape your dash.
Level 3QiyanaLevel 3 with all elements online you out-burst her in the window after her stun is spent.
Levels 4-5QiyanaLevels 4-5 you dictate trades and freeze to deny her safe stack-farming.
Level 6QiyanaLevel 6 your Audacity burst kills her before Tibbers whenever her Pyromania is grey.
First itemQiyanaFirst item you one-combo her from stealth the moment her stun is on cooldown.
Two+ itemsQiyanaAt 2+ items her total lack of mobility lets you out-position and pick her every fight.

Early game (levels 1–5)

Level 1 tips to Annie: her point-and-click Q pokes and stacks Pyromania while you have no attuned element or range to trade back, so play for XP and dodge the stun line. Watch her stack counter obsessively — the danger is entirely in that charged stun, not her raw stats.

Read the rest of this matchup

The full Qiyana vs Annie report continues with the mid-game plan, the late-game and teamfight plan, every power spike to play around, and the win conditions for both sides — plus cooldown tracking and the live enemy-jungle tracker inside the app.

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Related guides

Playing the other side? Annie vs Qiyana guide →
All Qiyana mid lane matchups →